(FRFSE, FR-FSE) The fast relaxation fast spin echo sequence provides high signal intensity of fluids even with short repetition times, and can be used with parallel imaging techniques for short breath hold imaging or respiratory gating for free-breathing, high isotropic resolution MR imaging. After signal decay at the end of the echo train, a negative 90° pulse align spins with long T2 from the transverse plane to the longitudinal plane, leading to a much faster recovery of tissues with long T2 time to the equilibrium and thus better contrast between tissues with long and short T2.
Fast relaxation FSE has advantages also for volumetric imaging as the TR can be substantially reduced and thus the scan time. The sequence can be post processed with maximum intensity projection, surface or volume rendering algorithms to visualize anatomical details in brain or spine MRI. Cerebro spinal fluid pulsation artifacts, often problematic in the cervical or thoracic spine may be reduced by radial sampling, in particular when combined with acquisitions of the PROPELLER type.

See also Fast spin echo, Driven Equilibrium.

Fractional Nex imaging (GE Healthcare term for imaging with a Nex value less than 1) benefits from the conjugate symmetry of the k-space to reduce the number of phase encoding acquisitions. With fractional Nex imaging (similar to partial Fourier or Half Scan), just over half of the data are acquired and the data from the lower part of k-space are used to fill the upper part, without sampling the upper part. Fractional Nex imaging sequences use a number of excitations values between 0.5 and 1. These values are a bit misleading, because the number of phase encoding steps is reduced, and not the NEX.
Fractional Nex imaging reduces the scan time considerable, by preserving the same contrast between the tissues. The effect by acquiring fewer data points is that the signal to noise ratio decreases.

See also acronyms for 'partial averaging//fractional Nex imaging' from different manufacturers.

(ISIS) Image selected in vivo spectroscopy is used as a localization sequence to provide complete gradient controlled three-dimensional localization with a reduced number of sequence cycles, e.g. for in vivo 31P spectroscopy. The ISIS method generates three 180° pulses prior to a 90° pulse, after which the free induction decay is recorded. Specific 180° pulses (slice-selective) are combined and the FID's added or subtracted to generate a spectrum.
An advantage of the ISIS method is that the magnetization (before the final 90° pulse) is predominantly along the z-axis and so T2 effects are relatively small. This explains the value of this technique for 31P data acquisition, because some phosphorus metabolites (e.g. ATP) have short T2 values.
A disadvantage is that eight acquisitions are required to accomplish the spatial localization, therefore the sequence cannot be used for localized shimming. Another problem, because any variation between these data collections (for example, due to movement) will degrade these applications, can be solved by incorporating outer volume suppression techniques such as OSIRIS (modified ISIS).

A gradient echo is generated by using a pair of bipolar gradient pulses. The gradient field is negatively pulsed, causing the spins of the xy-magnetization to dephase. A second gradient pulse is applied with the opposite polarity. During the pulsing, the spins that dephased begin to rephase and generate a gradient echo.
Spoiling can be accomplished by RF or a gradient. The incoherent RF spoiled type of a gradient echo sequence use a continuous shifting of the RF pulse to spoil the residual transverse magnetization. The phase of the RF excitation and receiver channel are varied pseudo randomly with each excitation cycle to prevent the xy magnetization from achieving steady state. T2* does not dominate image contrast, so T1 and PD weighting is practical. This method is effective and can be used to achieve a shorter TR, due to a lack of additional gradients. Spoiling eliminates the effect of the remaining xy-magnetization and leads to steady state longitudinal magnetization. These sequences can be used for breath hold, dynamic imaging and in cine and volume acquisitions.

From MagneVu;
The MagneVu 1000 is a compact, robust, and portable, permanent magnet MRI system and operates without special shielding or costly site preparation.
This MRI device utilizes a patented non-homogeneous magnetic field image acquisition method to achieve high performance imaging. The MagneVu 1000 MRI scanner is designed for MRI of the extremities with the current specialty areas in diabetes and rheumatoid arthritis. Easy access is afforded for claustrophobic, pediatric, or limited mobility patients.
In August 1998 FDA marketing clearance and other regulatory approvals have been received.
Until 2008, over 130 devices in the US are in use. Some further developments of MagneVu's extremity scanner are: 'truly Plug n' Play MRI™' and iSiS ( which adds wireless capability to the second generation MV1000-XL).