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Result : Searchterm 'Contrast Agents' found in 17 terms [] and 118 definitions []
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Medical Imaging
 
The definition of imaging is the visual representation of an object. Medical imaging began after the discovery of x-rays by Konrad Roentgen 1896. The first fifty years of radiological imaging, pictures have been created by focusing x-rays on the examined body part and direct depiction onto a single piece of film inside a special cassette. The next development involved the use of fluorescent screens and special glasses to see x-ray images in real time.
A major development was the application of contrast agents for a better image contrast and organ visualization. In the 1950s, first nuclear medicine studies showed the up-take of very low-level radioactive chemicals in organs, using special gamma cameras. This medical imaging technology allows information of biologic processes in vivo. Today, PET and SPECT play an important role in both clinical research and diagnosis of biochemical and physiologic processes. In 1955, the first x-ray image intensifier allowed the pick up and display of x-ray movies.
In the 1960s, the principals of sonar were applied to diagnostic imaging. Ultrasonic waves generated by a quartz crystal are reflected at the interfaces between different tissues, received by the ultrasound machine, and turned into pictures with the use of computers and reconstruction software. Ultrasound imaging is an important diagnostic tool, and there are great opportunities for its further development. Looking into the future, the grand challenges include targeted contrast agents, real-time 3D ultrasound imaging, and molecular imaging.
Digital imaging techniques were implemented in the 1970s into conventional fluoroscopic image intensifier and by Godfrey Hounsfield with the first computed tomography. Digital images are electronic snapshots sampled and mapped as a grid of dots or pixels. The introduction of x-ray CT revolutionised medical imaging with cross sectional images of the human body and high contrast between different types of soft tissue. These developments were made possible by analog to digital converters and computers. The multislice spiral CT technology has expands the clinical applications dramatically.
The first MRI devices were tested on clinical patients in 1980. The spread of CT machines is the spur to the rapid development of MRI imaging and the introduction of tomographic imaging techniques into diagnostic nuclear medicine. With technological improvements including higher field strength, more open MRI magnets, faster gradient systems, and novel data-acquisition techniques, MRI is a real-time interactive imaging modality that provides both detailed structural and functional information of the body.
Today, imaging in medicine has advanced to a stage that was inconceivable 100 years ago, with growing medical imaging modalities:
Single photon emission computed tomography (SPECT)
Positron emission tomography (PET)

All this type of scans are an integral part of modern healthcare. Because of the rapid development of digital imaging modalities, the increasing need for an efficient management leads to the widening of radiology information systems (RIS) and archival of images in digital form in picture archiving and communication systems (PACS). In telemedicine, healthcare professionals are linked over a computer network. Using cutting-edge computing and communications technologies, in videoconferences, where audio and visual images are transmitted in real time, medical images of MRI scans, x-ray examinations, CT scans and other pictures are shareable.
See also Hybrid Imaging.

See also the related poll results: 'In 2010 your scanner will probably work with a field strength of', 'MRI will have replaced 50% of x-ray exams by'
Radiology-tip.comradDiagnostic Imaging
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Further Reading:
  Basics:
Image Characteristics and Quality
   by www.sprawls.org    
Multimodal Nanoparticles for Quantitative Imaging(.pdf)
Tuesday, 13 December 2011   by alexandria.tue.nl    
Medical imaging shows cost control problem
Tuesday, 6 November 2012   by www.mysanantonio.com    
  News & More:
iMPI: An Exploration of Post-Launch Advancements
Friday, 29 September 2023   by www.diagnosticimaging.com    
Advances in medical imaging enable visualization of white matter tracts in fetuses
Wednesday, 12 May 2021   by www.eurekalert.or    
Positron Emission Tomographic Imaging in Stroke
Monday, 28 December 2015   by www.ncbi.nlm.nih.gov    
Multiparametric MRI for Detecting Prostate Cancer
Wednesday, 17 December 2014   by www.onclive.com    
Combination of MRI and PET imaging techniques can prevent second breast biopsy
Sunday, 29 June 2014   by www.news-medical.net    
3D-DOCTOR Tutorial
   by www.ablesw.com    
Searchterm 'Contrast Agents' was also found in the following services: 
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MemosomesInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Short name: Mn-EDTA-PP, generic name: Liposomes, central moiety: Mn2+, preclin. trade name: Memosomes
Memosomes are taken up by healthy Kupffer cells of the liver. Once in this cells, manganese (Mn+2) release slowly and diffuses into the adjoining hepatocytes. Normal liver tissue (not malignancies) is enhanced after application of this type of liposomes.

See also Liposomes, Hepatobiliary Contrast Agents, and Reticuloendothelial Contrast Agents.

See also Classifications, Characteristics, etc.
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• View the DATABASE results for 'Memosomes' (2).Open this link in a new window

MRI Resources 
Guidance - Blood Flow Imaging - Functional MRI - Quality Advice - Safety pool - Online Books
 
MetallofullerenesInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
The paramagnetic water-soluble metallofullerenes (Gd-fullerenols), which have strong T1 shortening effect, can be used as a novel core material of MRI contrast agents. Gadolinium endohedral metallofullerenes have been synthesized as polyhydroxyl forms (Gd@C82(OH)n, Gd-fullerenes) with the evaluation of their paramagnetic properties. The modification to the water-soluble forms is essential for the biomedical application of the metallofullerenes. The in vitro water proton relaxivity, R1 (the effect on 1/T1), of Gd-fullerenes is significantly higher (20-folds) than that of commercial MRI contrast agents - e.g. Gd-DTPA.
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• View the NEWS results for 'Metallofullerenes' (1).Open this link in a new window.
 
Further Reading:
  News & More:
A Single X-Ray Strike Is Enough to Destroy an Entire Molecule
Friday, 20 March 2020   by scitechdaily.com    
Searchterm 'Contrast Agents' was also found in the following services: 
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News  (49)  Resources  (7)  Forum  (8)  
 
Molecular Imaging
 
Molecular Imaging is a new diagnostic discipline to visualize biological processes.
Molecular magnetic resonance imaging (mMRI) offers the potential to image tissues at the cellular and subcellular level. Targeted MR contrast agents enhance the diagnostic specificity and range of molecular magnetic resonance imaging.
Other modalities that can be used for noninvasive molecular imaging:
•
Ultrasound;
•
optical imaging;
•
positron emission tomography (PET);
•
single photon emission computed tomography (SPECT).


See also Nanoparticle, Monocrystalline Iron Oxide Nanoparticle, Polycrystalline Iron Oxide Nanoparticles, Liposomes, Monoclonal Antibodies, Bimodal Imaging, Tumor Specific Agents, and Intracellular Contrast Agents.
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• View the NEWS results for 'Molecular Imaging' (28).Open this link in a new window.
 
Further Reading:
  Basics:
Multimodal Nanoparticles for Quantitative Imaging(.pdf)
Tuesday, 13 December 2011   by alexandria.tue.nl    
Molecular Magnetic Resonance Imaging(.pdf)
2005   by www.medical.siemens.com    
  News & More:
Smarter MRI diagnosis with nano MRI lamp
Monday, 6 February 2017   by www.eurekalert.org    
Molecular MRI technique gives early indication of cancer treatment effectiveness
Monday, 11 April 2016   by www.healthimaging.com    
Molecular imaging and radiochemistry: the importance of instrumentation. An interview with Professor Bjorn Wangler
Thursday, 4 February 2016   by www.news-medical.net    
Positron Emission Tomographic Imaging in Stroke
Monday, 28 December 2015   by www.ncbi.nlm.nih.gov    
Potential and Limitations of Oxygen-17 MR Perfusion Measurements
Monday, 1 March 2004   by www.case.edu    
Searchterm 'Contrast Agents' was also found in the following services: 
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Radiology  (46) Open this link in a new windowUltrasound  (75) Open this link in a new window
Monoclonal AntibodiesInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
(McAb) Monoclonal antibodies are used for tumor detection and localization in nuclear medicine. In MRI, monoclonal antibodies labeled with paramagnetic or superparamagnetic particles are being studied for targeting tumors, for example contrast agent containing gadolinium attached to a targeting antibody. The antibody would bind to a specific target (e.g., a metastatic melanoma cell) while the gadolinium would increase the MRI signal. Further developments are MRI contrast agents that specifically target glucose receptors on tumor cells; coupled with the high spatial resolution of high field MRI devices, these agents have potentials to detect small tumor foci.
The monoclonal antibody manufacturers produce a wide variety of ligands, which can be directed against a multiplicity of pathologic molecular targets. MRI enhanced with targeted contrast agents can be used for molecular imaging.
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Further Reading:
  News & More:
Measuring mAbs with magnetic resonance can help regulatory testing
Thursday, 23 April 2015   by www.biopharma-reporter.com    
Repligen - Eyeing Sustainable Profitability
Monday, 31 October 2011   by www.rttnews.com    
MRI Resources 
Jobs pool - MR Myelography - MRI Technician and Technologist Career - Crystallography - Veterinary MRI - Artifacts
 
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