(MRI) Magnetic resonance imaging is a noninvasive medical imaging technique that uses the interaction between radio frequency pulses, a strong magnetic field and body tissue to obtain images of slices/planes from inside the body. These magnets generate fields from approx. 2000 times up to 30000 times stronger than that of the Earth. The use of nuclear magnetic resonance principles produces extremely detailed pictures of the body tissue without the need for x-ray exposure and gives diagnostic information of various organs.
Measured are mobile hydrogen nuclei (protons are the hydrogen atoms of water, the 'H' in H20), the majority of elements in the body. Only a small part of them contribute to the measured signal, caused by their different alignment in the magnetic field. Protons are capable of absorbing energy if exposed to short radio wave pulses (electromagnetic energy) at their resonance frequency. After the absorption of this energy, the nuclei release this energy so that they return to their initial state of equilibrium.
This transmission of energy by the nuclei as they return to their initial state is what is observed as the MRI signal. The subtle differing characteristic of that signal from different tissues combined with complex mathematical formulas analyzed on modern computers is what enables MRI imaging to distinguish between various organs. Any imaging plane, or slice, can be projected, and then stored or printed.
The measured signal intensity depends jointly on the spin density and the relaxation times (T1 time and T2 time), with their relative importance depending on the particular imaging technique and choice of interpulse times. Any motion such as blood flow, respiration, etc. also affects the image brightness.
Magnetic resonance imaging is particularly sensitive in assessing anatomical structures, organs and soft tissues for the detection and diagnosis of a broad range of pathological conditions. MRI pictures can provide contrast between benign and pathological tissues and may be used to stage cancers as well as to evaluate the response to treatment of malignancies. The need for biopsy or exploratory surgery can be eliminated in some cases, and can result in earlier diagnosis of many diseases.

See also MRI History and Functional Magnetic Resonance Imaging (fMRI).

Means to confine the region of strong magnetic field surrounding a magnet; most commonly the use of material with high permeability (passive shielding) or by employing secondary counteracting coils outside of the primary coils (active shielding). The high permeability material can be employed in the form of a yoke immediately surrounding the magnet (self-shielding) or installed in the walls of a room as full or partial room-shielding. Unlike shielding ionizing radiation, for example, magnetic shielding can only be accomplished by forcing the unavoidable magnetic return flux through more confined areas or structures, not by absorbing it.

See also Radio Frequency Shielding Radio Frequency Shielding, and Faraday cage.

See also the related poll result: 'Most outages of your scanning system are caused by failure of'

(MTC) This MRI method increases the contrast by removing a portion of the total signal in tissue. An off resonance radio frequency (RF) pulse saturates macromolecular protons to make them invisible (caused by their ultra-short T2* relaxation times). The MRI signal from semi-solid tissue like brain parenchyma is reduced, and the signal from a more fluid component like blood is retained.
E.g., saturation of broad spectral lines may produce decreases in intensity of lines not directly saturated, through exchange of magnetization between the corresponding states; more closely coupled states will show a greater resulting intensity change. Magnetization transfer techniques make demyelinated brain or spine lesions (as seen e.g. in multiple sclerosis) better visible on T2 weighted images as well as on gadolinium contrast enhanced T1 weighted images.
Off resonance makes use of a selection gradient during an off resonance MTC pulse. The gradient has a negative offset frequency on the arterial side of the imaging volume (caudally more off resonant and cranially less off resonant). The net effect of this type of pulse is that the arterial blood outside the imaging volume will retain more of its longitudinal magnetization, with more vascular signal when it enters the imaging volume. Off resonance MTC saturates the venous blood, leaving the arterial blood untouched.
On resonance has no effect on the free water pool but will saturate the bound water pool and is the difference in T2 between the pools. Special binomial pulses are transmitted causing the magnetization of the free protons to remain unchanged. The z-magnetization returns to its original value. The spins of the bound pool with a short T2 experience decay, resulting in a destroyed magnetization after the on resonance pulse.

See also Magnetization Transfer.

An undesirable background interference or disturbance that affects image quality.
The Noise is commonly characterized by the standard deviation of signal intensity in the image of a uniform object (phantom) in the absence of artifacts. The measured noise may depend on the particular phantom used due to variable effects on the Q of the receiver coil.
Noisy images appear when the SNR-Rate is too low - this is induced by the operator. Image artifacts and RF noise can often be caused by the presence and/or operation of a medical device in the MR environment. There are various noise sources in any electronic system, including Johnson noise, shot noise, thermal noise. Materials produce their own characteristic static magnetic field that can perturb the relationship between position and frequency essential to accurate image reconstruction.
RF noise, which often appears as static on the image, can be caused by a medical device located anywhere in the MR procedure room. RF noise is a result of excessive electromagnetic emissions from the medical device that interfere with the proper operation of the MR scanner. Since the MR procedure room is shielded from extraneous RF fields entering the room (Faraday cage), operation of electromagnetically noisy equipment outside the room does not typically affect the MR scanner.

See Signal to Noise Ratio and Radio Frequency Noise Artifact.

This pulse affects all of the tissue within the transmitting coil. It is only used for MTC at a frequency distant from the Larmor frequency or if another method is selected to define slices like 3D acquisition.