Chemical shift depends on the nucleus and its environment and is defined as nuclear shielding / applied magnetic field. Nuclei are shielded by a small magnetic field caused by circulating electrons, termed nuclear shielding. The strength of the shield depends on the different molecular environment in that the nucleus is embedded. Nuclear shielding is the difference between the magnetic field at the nucleus and the applied magnetic field.
Chemical shift is measured in parts per million (ppm) of the resonance frequency relative to another or a standard resonance frequency.
The major part of the MR signal comes from hydrogen protons; lipid protons contribute a minor part. The chemical shift between water and fat nuclei is about 3.5 ppm (~220 Hz; 1.5T). Through this difference in resonance frequency between water and fat protons at the same location, a misregistration (dislocation) by the Fourier Transformation take place, when converting MR signals from frequency to spatial domain. This effect is called chemical shift artifact or chemical shift misregistration artifact.
During frequency encoding, fat protons precess slower than water protons in the same slice because of their magnetic shielding. Through the difference in resonance frequency between water and fat, protons at the same location are misregistrated (dislocated) by the Fourier transformation, when converting MRI signals from frequency to spatial domain. This chemical shift misregistration cause accentuation of any fat-water interfaces along the frequency axis and may be mistaken for pathology. Where fat and water are in the same location, this artifact can be seen as a bright or dark band at the edge of the anatomy.
Protons in fat and water molecules are separated by a chemical shift of about 3.5 ppm. The actual shift in Hertz (Hz) depends on the magnetic field strength of the magnet being used. Higher field strength increases the misregistration, while in contrast a higher gradient strength has a positive effect. For a 0.3 T system operating at 12.8 MHz the shift will be 44.8 Hz compared with a 223.6 Hz shift for a 1.5 T system operating at 63.9 MHz.
Keyhole imaging is used for dynamic imaging with contrast medium. The advantage is that the keyhole technique increases temporal resolution without a loss of spatial resolution by limited data acquisition. Keyhole Fourier imaging updates the low spatial frequencies of the original full, high-resolution data set. The high spatial frequency content of the image is constant in time so that its updating would be unnecessary. The high spatial frequency data is acquired from a baseline image, for example, before injection of a contrast agent.
After contrast injection, only the lower spatial frequency data is acquired because, there is no change in the tissue that is responsible for the higher frequency spatial variation in the image.
(MR) Resonance phenomenon resulting in the absorption and/or emission of electromagnetic energy by nuclei (for that reason also nuclear magnetic resonance) or electrons in a static magnetic field, after excitation by a suitable RF magnetic field.
The peakresonance frequency is proportional to the magnetic field, and is given by the Larmor equation. Only unpaired electrons or nuclei with a spin exhibit magnetic resonance. The absorption or emission of energy by atomic nuclei in an external magnetic field after the application of RF excitation pulses using frequencies, which satisfy the conditions of the Larmor equation.
The magnetic resonance phenomenon may be used in one of these ways:
By manipulation of the external field (application of gradient fields), the resonance frequency can become dependent on spatial location, and hence images may be generated (MRI).
The effect of the electron cloud in any atom or molecule is to slightly shield the nucleus from the external field, thus giving any chemical species a characteristic frequency. This gives rise to 'spectra' where nuclei in a molecule give rise to specific signals, thus facilitating the detection of individual chemicals by means of their frequencyspectra (MRS)
According to Shannon's sampling theorem, the samplingfrequency should be twice the frequency being sampled. The maximum measurable frequency is therefore equal to one half the sampling rate. This is the so-called Nyquist limit. When the frequency is higher than the Nyquist limit, aliasing occurs.
• View the DATABASE results for 'Nyquist Limit' (3).