The magnetic isocenter is the center point of a magnetic field, the origin of the coordinate system (x, y, z) = (0, 0 ,0). In case of a cylindrical bore magnet type, the magnetic isocenter is at the center of the bore.

Fat suppression is the process of utilizing specific MRI parameters to remove the deleterious effects of fat from the resulting images , e.g. with STIR, FAT SAT sequences, water selective (PROSET WATS - water only selection, also FATS - fat only selection possible) excitation techniques, or pulse sequences based on the Dixon method.
Spin magnetization can be modulated by using special RF pulses. CHESS or its variations like SPIR, SPAIR (Spectral Selection Attenuated Inversion Recovery) and FAT SAT use frequency selective excitation pulses, which produce fat saturation.
Fat suppression techniques are nearly used in all body parts and belong to every standard MRI protocol of joints like knee, shoulder, hips, etc. Imaging of, e.g. the foot can induce bad fat suppression with SPIR/FAT SAT due to the asymmetric volume of this body part. The volume of the foot alters the magnetic field to a different degree than the smaller volume of the lower leg affecting the protons there. There is only a small band of tissue where the fat protons are precessing at the frequency expected, resulting in frequency selective fat saturation working only in that area. This can be corrected by volume shimming or creating a more symmetrical volume being imaged with water bags.
Even with their longer scan time and motion sensitivity, STIR (short T1/tau inversion recovery) sequences are often the better choice to suppress fat. STIR images are also preferred because of the decreased sensitivity to field inhomogeneities, permitting larger fields of views when compared to fat suppressed images and the ability to image away from the isocenter.
See also Knee MRI.
Sequences based on Dixon turbo spin echo (fast spin echo) can deliver a significant better fat suppression than conventional TSE/FSE imaging.

Quick Overview

A disturbance of the field homogeneity, because of magnetic material (inside or outside the patient), technical problems or scanning at the edge of the field.
When images were obtained in a progression from the center to the edge of the coil, the homogeneity of the field observed by the imaged volume, changes when the distance from the center of the volume increase. The same problem appears by scanning at a distance from the isocenter in left-right direction or too large field of view.
There are different types of bad image quality, the images are noisy, distorted or the fat suppression doesn't work because of badly set shim currents.
E.g. by using an IR sequence, changes in the T1 recovery rates of the tissues are involved. The inversion time at the center of the imaged volume is appropriate to suppress fat, but at the edge of the coil the same inversion time is sufficient to suppress water. Since the inversion time is not changed, the T1 recovery rates will increase.

Take a smaller imaging volume (and for fat suppression a volume shimming), take care that the imaged region is at the center of the coil and that no magnetic material is inside the imaging volume.

(FOV) Defined as the size of the two or three dimensional spatial encoding area of the image. Usually defined in units of mm². The FOV is the square image area that contains the object of interest to be measured. The smaller the FOV, the higher the resolution and the smaller the voxel size but the lower the measured signal. Useful for decreasing the scantime is a field of view different in the frequency and phase encoding directions (rectangular field of view - RFOV).
The magnetic field homogeneity decreases as more tissue is imaged (greater FOV). As a result the precessional frequencies change across the imaging volume. That can be a problem for fat suppression imaging. This fat is precessing at the expected frequency only in the center of the imaging volume. E.g. frequency specific fat saturation pulses become less effective when the field of view is increased. It is best to use smaller field of views when applying fat saturation pulses.

Smaller FOV required higher gradient strength and concludes low signal. Therefore you have to find a compromise between these factors. The right choice of the field of view is important for MR image quality. When utilizing small field of views and scanning at a distance from the isocenter (more problems with artifacts) it is obviously important to ensure that the region of interest is within the scanning volume.
A smaller FOV in one direction is available with the function rectangular field of view (RFOV).

See also Field Inhomogeneity Artifact.

The incoherent gradient echo (gradient spoiled) type of sequence uses a continuous shifting of the RF pulse to spoil the remaining transverse magnetization. The transverse magnetization is destroyed by a magnetic field gradient. This results in a T1 weighted image. Spoiling can be accomplished by RF or a gradient.
Gradient spoiling occurs after each echo by using strong gradients in the slice-select direction after the frequency encoding and before the next RF pulse. Because spins in different locations in the magnet thereby experience a variety of magnetic field strengths, they will precess at differing frequencies; as a consequence they will quickly become dephased. Magnetic field gradients are not very efficient at spoiling the transverse steady state. To be effective, the spins must be forced to precess far enough to become phased randomly with respect to the RF excitation pulse. In clinical MRI machines, the field gradients are set up in such a way that they increase and decrease relative to the center of the magnet; the magnetic field at the magnet 'isocenter' does not change.
The T1 weighting increases with the flip angle and the T2* weighting increases with echo time (TE). Typical repetition time (TR) are 30-500 ms and TE less than 15 ms.

See also Ernst Angle.