(GE) An echo signal generated from a free induction decay by means of a bipolar switched magnetic gradient. The echo is produced by reversing the direction of a magnetic field gradient or by applying balanced pulses of magnetic field gradient before and after a refocusing RF pulse so as to cancel out the position dependent phase shifts that have accumulated due to the gradient.
In the latter case, the gradient echo is generally adjusted to be coincident with the RF spin echo. When the RF and gradient echoes are not coincident, the time of the gradient echo is denoted echo time (TE) and the difference in time between the echoes is denoted time difference (TD).
Gradient echo does not refocus the effects of main field inhomogeneity and therefore is generally used with a short echo time. Disadvantages of gradient echo imaging are compromised anatomic details and artifacts in regions with varying susceptibility e.g. between the air-containing sinuses and brain and especially between haemorrhages and normal tissue.

See also Susceptibility Artifact.

Coherent gradient echo sequences can measure the free induction decay (FID), generated just after each excitation pulse or the echo formed prior to the next pulse. Coherent gradient echo sequences are very sensitive to magnetic field inhomogeneity. An alternative to spoiling is to incorporate residual transverse magnetization directly into the longitudinal steady state. These GRE sequences use a refocusing gradient in the phase encoding direction during the end module to maximize remaining transverse (xy) magnetization at the time when the next excitation is due, while the other two gradients are, in any case, balanced.
When the next excitation pulse is sent into the system with an opposed phase, it tilts the magnetization in the -a direction. As a result the z-magnetization is again partly tilted into the xy-plane, while the remaining xy-magnetization is tilted partly into the z-direction.
A fully refocused sequence with a properly selected and uniform f would yield higher signal, especially for tissues with long T2 relaxation times (high water content) so it is used in angiographic, myelographic or arthrographic examinations and is used for T2* weighting. The repetition time for this sequence has to be short. With short TR, coherent GE is also useable for breath hold and 3D technique. If the repetition time is about 200 msec there's no difference between spoiled or unspoiled GE. T1 weighting is better with spoiled techniques.
The common types include GRASS, FISP, FAST, and FFE.
The T2* component decreases with long TR and short TE. The T1 time is controlled by flip angle. The common TR is less than 50 ms and the common TE less than 15 ms
Other types have stronger T2 dependence but lower SNR. They include SSFP, CE-FAST, PSIF, and CE-FFE-T2.
Examples of fully refocused FID sequences are TrueFISP, bFFE and bTFE.

The principal contraindications of the MRI procedure are mostly related to the presence of metallic implants in a patient. The risks of MRI scans increase with the used field strength. In general, implants are becoming increasingly MR safe and an individual evaluation is carried out for each case.

Some patients should not be examined in MRI machines, or come closer than the 5 Gauss line to the system.

Absolute Contraindications for the MRI scan:
Patients with absolute contraindications should not be examined or only with special MRI safety precautions. Patients with an implanted cardiac pacemaker have been scanned on rare occasions, but pacemakers are generally considered an absolute contraindication. Relative contraindications may pose a relative hazard, and the type and location of an implant should be assessed prior to the MRI examination.

Relative Contraindications for the MRI scan:
Osteosynthesis material is usually anchored so well in the patients that no untoward effect will result. Another effect on metal parts in the patient's body is the heating of these parts through induction. In addition, image quality may be severely degraded. The presence of other metallic implants such as surgical clips etc. should be made known to the MRI operators. Most of these materials are non-magnetic, but if magnetic, they can pose a hazard.

See also MRI safety, Pregnancy, Claustrophobia and Tattoos.