Short name: P760, chemical compound: tetraazacyclododecanetetraacetic acid (DOTA), central moity: Gd P760 (Guerbet SA) is a low-diffusion gadolinium complex with a macrocyclic core based on a tetraazacyclododecanetetraacetic acid (DOTA)
structure, which is substituted with bulky hydrophilic
groups.
The relaxivity of P760 at 0.47 T is very high compared to Gd-DOTA.
The France-based Guerbet Group is highly specialized in contrast media for medical imaging. Its strategic goal is to be a key player in this market. Products include Dotarem (Magnetic Resonance Imaging) and Xenetix (X-ray Imaging).
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