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Phase Coherence
 
A term describing the degree, to which precessing nuclear spins are synchronous.
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(MRA) Magnetic resonance angiography is a medical imaging technique to visualize blood filled structures, including arteries, veins and the heart chambers. This MRI technique creates soft tissue contrast between blood vessels and surrounding tissues primarily created by flow, rather than displaying the vessel lumen. There are bright blood and black blood MRA techniques, named according to the appearance of the blood vessels. With this different MRA techniques both, the blood flow and the condition of the blood vessel walls can be seen. Flow effects in MRI can produce a range of artifacts. MRA takes advantage of these artifacts to create predictable image contrast due to the nature of flow.
Technical parameters of the MRA sequence greatly affect the sensitivity of the images to flow with different velocities or directions, turbulent flow and vessel size.
This are the three main types of MRA:
All angiographic techniques differentially enhance vascular MR signal. The names of the bright blood techniques TOF and PCA reflect the physical properties of flowing blood that were exploited to make the vessels appear bright. Contrast enhanced magnetic resonance angiography creates the angiographic effect by using an intravenously administered MR contrast agent to selectively shorten the T1 of blood and thereby cause the vessels to appear bright on T1 weighted images.
MRA images optimally display areas of constant blood flow-velocity, but there are many situations where the flow within a voxel has non-uniform speed or direction. In a diseased vessel these patterns are even more complex. Similar loss of streamline flow occurs at all vessel junctions and stenoses, and in regions of mural thrombosis. It results in a loss of signal, due to the loss of phase coherence between spins in the voxel.
This signal loss, usually only noticeable distal to a stenosis, used to be an obvious characteristic of MRA images. It is minimized by using small voxels and the shortest possible TE. Signal loss from disorganized flow is most noticeable in TOF imaging but also affects the PCA images.
Indications to perform a magnetic resonance angiography (MRA):
Detection of aneurysms and dissections
Evaluation of the vessel anatomy, including variants
Blockage by a blood clot or stenosis of the blood vessel caused by plaques (the buildup of fat and calcium deposits)

Conventional angiography or computerized tomography angiography (CT angiography) may be needed after MRA if a problem (such as an aneurysm) is present or if surgery is being considered.

See also Magnetic Resonance Imaging MRI.
 
Images, Movies, Sliders:
 CE-MRA of the Carotid Arteries Colored MIP  Open this link in a new window
    
SlidersSliders Overview

 CE MRA of the Aorta  Open this link in a new window
    
SlidersSliders Overview

 TOF-MRA Circle of Willis Inverted MIP  Open this link in a new window
    

 PCA-MRA 3D Brain Venography Colored MIP  Open this link in a new window
    

 Circle of Willis, Time of Flight, MIP  Open this link in a new window
    
SlidersSliders Overview

 
Radiology-tip.comradCT Angiography,  Angiogram
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Medical-Ultrasound-Imaging.comVascular Ultrasound,  Intravascular Ultrasound
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Further Reading:
  Basics:
Magnetic resonance angiography: current status and future directions
Wednesday, 9 March 2011   by www.jcmr-online.com    
MR–ANGIOGRAPHY(.pdf)
  News & More:
3-D-printed model of stenotic intracranial artery enables vessel-wall MRI standardization
Friday, 14 April 2017   by www.eurekalert.org    
Conventional MRI and MR Angiography of Stroke
2012   by www.mc.vanderbilt.edu    
MR Angiography Highly Accurate In Detecting Blocked Arteries
Thursday, 1 February 2007   by www.sciencedaily.com    
MRI Resources 
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Phase Shift
 
The phase shift is the loss of phase coherence in precessing spins. Vascular spins move at variable velocities; faster flow undergo a stronger phase shift than slower flowing spins.
 
Images, Movies, Sliders:
 PCA-MRA 3D Brain Venography Colored MIP  Open this link in a new window
    

 
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Rephasing
 
The process of returning out of phase magnetic moments back into phase coherence. Caused either by rapidly reversing a magnetic gradient (Field Echo) or by applying a 180° RF pulse (Spin Echo). In the spin echo pulse sequence this action effectively cancels out the spurious T2* information from the signal.

See also Spin Echo Sequence and Gradient Echo Sequence.
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Steady State Free PrecessionInfoSheet: - Sequences - 
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(SFP or SSFP) Steady state free precession is any field or gradient echo sequence in which a non-zero steady state develops for both components of magnetization (transverse and longitudinal) and also a condition where the TR is shorter than the T1 and T2 times of the tissue. If the RF pulses are close enough together, the MR signal will never completely decay, implying that the spins in the transverse plane never completely dephase. The flip angle and the TR maintain the steady state. The flip angle should be 60-90° if the TR is 100 ms, if the TR is less than 100 ms, then the flip angle for steady state should be 45-60°.
Steady state free precession is also a method of MR excitation in which strings of RF pulses are applied rapidly and repeatedly with interpulse intervals short compared to both T1 and T2. Alternating the phases of the RF pulses by 180° can be useful. The signal reforms as an echo immediately before each RF pulse; immediately after the RF pulse there is additional signal from the FID produced by the pulse.
The strength of the FID will depend on the time between pulses (TR), the tissue and the flip angle of the pulse; the strength of the echo will additionally depend on the T2 of the tissue. With the use of appropriate dephasing gradients, the signal can be observed as a frequency-encoded gradient echo either shortly before the RF pulse or after it; the signal immediately before the RF pulse will be more highly T2 weighted. The signal immediately after the RF pulse (in a rapid series of RF pulses) will depend on T2 as well as T1, unless measures are taken to destroy signal refocusing and prevent the development of steady state free precession.
To avoid setting up a state of SSFP when using rapidly repeated excitation RF pulses, it may be necessary to spoil the phase coherence between excitations, e.g. with varying phase shifts or timing of the exciting RF pulses or varying spoiler gradient pulses between the excitations.
Steady state free precession imaging methods are quite sensitive to the resonant frequency of the material. Fluctuating equilibrium MR (see also FIESTA and DRIVE)and linear combination SSFP actually use this sensitivity for fat suppression. Fat saturated SSFP (FS-SSFP) use a more complex fat suppression scheme than FEMR or LCSSFP, but has a 40% lower scan time.
A new family of steady state free precession sequences use a balanced gradient, a gradient waveform, which will act on any stationary spin on resonance between 2 consecutive RF pulses and return it to the same phase it had before the gradients were applied.
This sequences include, e.g. Balanced Fast Field Echo - bFFE, Balanced Turbo Field Echo - bTFE, Fast Imaging with Steady Precession - TrueFISP and Balanced SARGE - BASG.

See also FIESTA.
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Further Reading:
  News & More:
Comparison of New Methods for Magnetic Resonance Imaging of Articular Cartilage(.pdf)
2002
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