Short name: PION, generic name: Polycrystalline iron oxide nanoparticles, central moiety: Fe2+/Fe3+, relaxivity: T2*enhanced, r2//r1=4.4, r2//r1=7
A substance under development (preclin.) as an RES-directed MRIcontrast agent (larger particles = DDM 128, PION-ASF) for MR lymphography and the detection of liver lesions.
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Molecular Imaging is a new diagnostic discipline to visualize biological processes.
Molecular magnetic resonance imaging (mMRI) offers the potential to image tissues at the cellular and subcellular level. Targeted MR contrast agents enhance the diagnostic specificity and range of molecular magnetic resonance imaging.
Other modalities that can be used for noninvasive molecular imaging:
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Ultrasound;
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optical imaging;
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positron emission tomography (PET);
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single photon emission computed tomography (SPECT).
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