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Biograph mMR
 
www.healthcare.siemens.com/magnetic-resonance-imaging/mr-pet-scanner/biograph-mmr FDA cleared and CE Mark 2011.
The Biograph mMR has a fully-integrated design for simultaneous PET/MRI imaging. The dedicated hardware includes solid-state, avalanche photodiode PET detector and adapted, PET-compatible MR coils.
The possibility of truly simultaneous operation allows the acquisition of several magnetic resonance imaging (MRI) sequences during the positron emission tomography (PET) scan, without increasing the examination time.
See also Hybrid Imaging.
Device Information and Specification
CLINICAL APPLICATION
Whole Body
CONFIGURATION
Simultaneous PET/MRI
3 Tesla
Full range of MRI coils
CHANNELS
up to 32
PET ACQUISITION MODES
3D
MRI ACQUISITION MODES
2D/3D, spectroscopy;; iPAT, GRAPPA (k-space), noncontrast angiography, radial motion compensation
PET EFFECTIVE AXIAL FOV
26 cm (typical overlap 23%)
MRI FOV
A-P 45, R-L 50, H-F 50 cm
PET RING DIAMETER
65.6 cm
PATIENT SCAN RANGE
199 cm
HORIZONTAL SPEED
200 mmsec
TABLE CAPACITY
200 kg
PET DETECTOR
Solid state, 4032 avalanche photo diodes
DETECTOR SCINTILLATION MATERIAL
LSO, 28672 crystals
CRYSTAL SIZE
4 x 4 x 20 mm
MAGNET WEIGHT
9000 kg
DIMENSION H*W*D (gantry included)
335 x 230 x 242 cm (finshed covers)
5-GAUSS FRINGE FIELD
2.6 m / 4.6 m
CRYOGEN USE
Zero boil off rate, approx. 10 years
COOLING SYSTEM
PET system: water; MRI system: water
up to 200 T/m/s
MAX. AMPLITUDE
45 mT/m
Aautomatic, patient specific shim; active shim 3 linear and 5 non-linear channels (seond order)
POWER REQUIREMENTS
380 / 400 / 420 / 440 / 460 / 480 V, 3-phase + ground; Total system 110kW
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Further Reading:
  Basics:
Performance Measurements of the Siemens mMR Integrated Whole-Body PET/MR Scanner
Friday, 11 November 2011   by jnm.snmjournals.org    
Global Trends in Hybrid Imaging
Monday, 1 November 2010   by pubs.rsna.org    
  News & More:
Positron Emission Tomographic Imaging in Stroke
Monday, 28 December 2015   by www.ncbi.nlm.nih.gov    
A world's first in imaging – integrated whole-body molecular MR system available for clinical use testing
Thursday, 18 November 2010   by www.siemens.com    
FDA Clears New System to Perform Simultaneous PET, MRI Scans
Friday, 10 June 2011   by www.prnewswire.com    
Frost & Sullivan Award Underlines Siemens Healthcare's Contribution to New Product Innovation in the North American Medical Imaging Market
Wednesday, 13 July 2011   by multivu.prnewswire.com    
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Radiology  (2) Open this link in a new windowUltrasound  (1) Open this link in a new window
Bipolar Gradient Pulse
 
Bipolar gradients are two gradients with the same magnitude but opposite gradient direction. A bipolar gradient pulse is produced if one of the bipolar gradients is switched e.g., in negative direction and then switched in the opposite direction for an equivalent amount of time.
Bipolar gradients are used e.g. in phase contrast and diffusion weighted sequences. A bipolar gradient pulse pair produces a phase shift, which depends on the velocity component along this gradient. Motion along a bipolar gradient pulse pair results in a flow-induced phase shift of the transverse magnetization. The bipolar gradient pulse pair will not affect stationary spins. The amount of phase shifts depends on the area of each gradient pulse, and distance between the pulses. An echo occurring after such a gradient is flow compensated for velocity. A slight shift in the balance of this gradient will introduce a defined flow sensitivity of the pulse sequence.
 
Images, Movies, Sliders:
 PCA-MRA 3D Brain Venography Colored MIP  Open this link in a new window
    

 
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MRI Resources 
Databases - Software - Mobile MRI Rental - Supplies - Movies - Spectroscopy
 
Black Blood MRAForum -
related threadsInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.MRI Resource Directory:
 - Cardiovascular Imaging -
 
With this magnetic resonance angiography technique flowing blood appears dark.
MR black blood techniques have been developed for cardiovascular imaging to improve segmentation of myocardium from the blood pool. Black blood MRA techniques decrease the signal from blood with reference to the myocardium and make it easier to perform cardiac chamber segmentation.
ECG gated spin echo sequences with presaturation pulses for magnetization preparation will show strong intravascular signal loss due to flow effects when appropriate imaging conditions including spatial presaturation are used. The sequence use the flow void effect as blood passes rapidly through the selected slice.
For dark blood preparation, a pair of nonselective and selective 180° inversion pulses are used, followed by a long inversion time to null signal from inflowing blood. A second selective inversion pulse can also be applied with short inversion time to null the fat signal. These in cardiac imaging used black blood techniques are referred to as double inversion recovery T1 measurement turbo spin echo or fast spin echo, and double-inversion recovery STIR.
 
Images, Movies, Sliders:
 Normal Dual Inversion Fast Spin-echo  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 
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Blood Flow ImagingMRI Resource Directory:
 - Blood Flow Imaging -
 
MR imaging techniques capable to provide maps of cerebral activity. All these techniques are based on indirect assessment of local cerebral haemodynamics that have been demonstrated to be closely related to cerebral activity.
Two kinds of techniques have been developed:
based on the assessment of the decrease in the content of deoxyhaemoglobin in local activated tissue that can be revealed as an increase of signal on T2* and T2 weighted sequences in which deoxyhaemoglobin has low signal (see Blood Oxygenation Level Dependent Contrast)
based on the time of flight or flow-related enhancement that is revealed either directly with T1 weighted images or through the use of modified angiographic bolus tracking techniques.
 
Images, Movies, Sliders:
 Circle of Willis, Time of Flight, MIP  Open this link in a new window
    
SlidersSliders Overview

 
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Further Reading:
  News & More:
Turbo-FLASH Based Arterial Spin Labeled Perfusion MRI at 7 T
Thursday, 20 June 2013   by www.plosone.org    
Non-invasive MRI technique distinguishes between Alzheimer's and frontotemporal dementia
Saturday, 18 June 2005   by www.eurekalert.org    
Searchterm 'Sequences' was also found in the following services: 
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Brain MRIForum -
related threadsMRI Resource Directory:
 - Brain MRI -
 
Brain imaging, magnetic resonance imaging of the head or skull, cranial magnetic resonance tomography (MRT), neurological MRI - they describe all the same radiological imaging technique for medical diagnostic.
Magnetic resonance imaging of the human brain includes the anatomic description and the detection of lesions. Special techniques like diffusion weighted imaging, functional magnetic resonance imaging (fMRI) and spectroscopy provide also information about the function and chemical metabolites of the brain. MRI provides detailed pictures of brain and nerve tissues in multiple planes without obstruction by overlying bones. Brain MRI is the procedure of choice for most brain disorders. It provides clear images of the brainstem and posterior brain, which are difficult to view on a CT scan. It is also useful for the diagnosis of demyelinating disorders (disorders such as multiple sclerosis (MS) that cause destruction of the myelin sheath of the nerve).
With this noninvasive procedure also the evaluation of blood flow and the flow of cerebrospinal fluid (CSF) is possible. Different MRA methods, also without contrast agents can show a venous or arterial angiogram. MRI can distinguish tumors, inflammatory lesions, and other pathologies from the normal brain anatomy. However, MRI scans are also used instead other methods to avoid the dangers of interventional procedures like angiography (DSA - digital subtraction angiography) as well as of repeated exposure to radiation as required for computed tomography (CT) and other X-ray examinations.
A (birdcage) bird cage coil achieves uniform excitation and reception and is commonly used to study the brain. Usually a brain MRI procedure includes FLAIR, T2 weighted and T1 weighted sequences in two or three planes.

See also Fetal MRI, Fluid Attenuation Inversion Recovery (FLAIR), Perfusion Imaging and High Field MRI.
See also Arterial Spin Labeling.
 
Images, Movies, Sliders:
 Brain MRI Images Axial T2  Open this link in a new window
      

 MRI of the Skull Base  Open this link in a new window
    
SlidersSliders Overview

 Anatomic Imaging of the Orbita  Open this link in a new window
      

 Brain MRI Images T1  Open this link in a new window
 MRI of the Brain Stem with Temoral Bone and Auditory System  Open this link in a new window
    
SlidersSliders Overview

 TOF-MRA Circle of Willis Inverted MIP  Open this link in a new window
    

 PCA-MRA 3D Brain Venography Colored MIP  Open this link in a new window
    

 
Medical-Ultrasound-Imaging.comA-Mode
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• View the NEWS results for 'Brain MRI' (32).Open this link in a new window.
 
Further Reading:
  Basics:
New MRI technique offers faster diagnosis of multiple sclerosis
Monday, 1 February 2016   by medicalxpress.com    
Ultra-high-field MRI reveals language centres in the brain in much more detail
Tuesday, 28 October 2014   by medicalxpress.com    
A Dutch study has revealed that as many as 13% of healthy adults may have some type of undiagnosed abnormality in the brain.
Sunday, 4 November 2007   by www.news-medical.net:80    
  News & More:
MRI Reveals Significant Brain Abnormalities Post-COVID
Monday, 21 November 2022   by neurosciencenews.com    
Combining genetics and brain MRI can aid in predicting chances of Alzheimer's disease
Wednesday, 29 June 2022   by www.sciencedaily.com    
Roundup: How Even Mild COVID Can Affect the Brain; This Many Daily Steps Improves Longevity; and More
Friday, 11 March 2022   by baptisthealth.net    
A low-cost and shielding-free ultra-low-field brain MRI scanner
Tuesday, 14 December 2021   by www.nature.com    
Large International Study Reveals Spectrum of COVID-19 Brain Complications
Tuesday, 9 November 2021   by www.itnonline.com    
Brain MRI-Based Subtypes of MS Predict Disability Progression, Treatment Response
Thursday, 13 May 2021   by www.neurologyadvisor.com    
New MRI method improves detection of disease changes in the brain's network
Thursday, 11 June 2020   by www.compute.dtu.dk    
New NeuroCOVID Classification System Uses MRI to Categorize Patients
Friday, 12 June 2020   by www.diagnosticimaging.com    
New MRI technique can 'see' molecular changes in the brain
Thursday, 5 September 2019   by medicalxpress.com    
Talking therapy or medication for depression: Brain scan may help suggest better treatment
Monday, 27 March 2017   by www.newsnation.in    
MRI identifies brain abnormalities in chronic fatigue syndrome patients
Wednesday, 29 October 2014   by www.eurekalert.org    
MRIs Useful in Tracking Depression in MS Patients
Tuesday, 1 July 2014   by www.hcplive.com    
Contrast agent linked with brain abnormalities on MRI
Tuesday, 17 December 2013   by www.sciencecodex.com    
MRIs Reveal Signs of Brain Injuries Not Seen in CT Scans
Tuesday, 18 December 2012   by www.sciencedaily.com    
Iron Deposits in the Brain May Be Early Indicator of MS
Wednesday, 13 November 2013   by www.healthline.com    
Migraine Sufferers Have Thicker Brain Cortex
Tuesday, 20 November 2007   by www.medicalnewstoday.com    
MRI Resources 
Functional MRI - Software - Non-English - Homepages - Chemistry - Brain MRI
 
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