The relaxation effect is the transition of an atom or molecule from a higher energy level to a lower one. The return of the excited proton from the high energy to the low energy level is associated with the loss of energy to the surrounding tissue. The T1 and T2 relaxation times define the way that the protons return to their resting levels after the initial radio frequency (RF) pulse. The T1 and T2 relaxation rates have an effect of the signal to noise ratio (SNR) of MR images.
The relaxation process is a result of both T1 and T2, and can be controlled by the dependency of one of the two biological parameters T1 and T2 in the recorded signal. A T1 weighted spin echo sequence is based on a short repetition time (TR) and a change of it will affect the acquisition time and the T1 weighting of the image. Increased TR results in improved SNR caused by longer recovering time for the longitudinal magnetization. Increased TE improves the T2 weighting, combined with a long TR (of several T1 times) to minimize the T1 effect.

Liver imaging with gadolinium contrast enhanced MRI is sometimes not sufficient for a reliable diagnosis of liver lesions. For this reasons, special liver Contrast agents that are targeted to the reticuloendothelial system (RES), have been developed to improve both detection and characterization of liver and spleen lesions. Reticuloendothelial Contrast Agents, as e.g. superparamagnetic iron oxides (SPIO), are taken up by healthy liver tissue but not tumors.
These RES targeted contrast agents provide a prolonged imaging window and enough time for high spatial resolution or multiple breath hold images. Reticuloendothelial contrast agents have an increased sensitivity for the detection of small liver lesions (e.g., metastases), compared with gadolinium enhanced MRI and spiral CT. At higher field strengths with an increased signal to noise ratio the susceptibility effect with iron oxide particles may be enhanced.
Other new agents (Gadobenate Dimeglumine, Gadoxetic Acid) have both an initial extracellular circulation and a delayed liver-specific uptake. Since a considerable part of these contrast agents is excreted in the bile, functional biliary imaging can diagnose biliary anomalies, postoperative bile leaks, and anastomotic strictures. Other agents, such as liposomes (with encapsulated Gd-DTPA) or DOTA complexes are in different development stages.

See also Hepatobiliary Contrast Agents, Gadolinium Oxide, Superparamagnetic Iron Oxide and Liposomes.

From GE Healthcare;
The GE Signa HDx MRI system is a whole body magnetic resonance scanner designed to support high resolution, high signal to noise ratio, and short scan times.
The 1.5T Signa HDx MR Systems is a modification of the currently marketed GE 1.5T machines, with the main difference being the change to the receive chain architecture that includes a thirty two independent receive channels, and allows for future expansion in 16 channel increments. The overall system has been improved with a simplified user interface and a single 23" liquid crystal display, improved multi channel surface coil connectivity, and an improved image reconstruction architecture known as the Volume Recon Engine (VRE).

From GE Healthcare;
The Signa HDx MRI system is GE's leading edge whole body magnetic resonance scanner designed to support high resolution, high signal to noise ratio, and short scan times.
Signa HDx 3.0T offers new technologies like ultra-fast image reconstruction through the new XVRE recon engine, advancements in parallel imaging algorithms and the broadest range of premium applications. The HD applications, PROPELLER (high-quality brain imaging extremely resistant to motion artifacts), TRICKS (contrast-enhanced angiographic vascular lower leg imaging), VIBRANT (for breast MRI), LAVA (high resolution liver imaging with shorter breath holds and better organ coverage) and MR Echo (high-definition cardiac images in real time) offer unique capabilities.

A signal to noise improvement method that is accomplished by taking the average of several FID`s made under similar conditions to suppress the effects of random variations or random artifacts. It is a common method to increase the SNR by averaging several measurements of the signal.
The number of averages is also referred to as the number of excitations (NEX) or the number of acquisitions (NSA). Doubling the number of acquisitions will increase the SNR by √2. The approximate amount of improvement in signal to noise (SNR) ratio is calculated as the square root of the number of excitations.
By using multiple averages, respiratory motion can be reduced in the same way that multiple averages increase the signal to noise ratio. NEX/NSA will increase SNR but will not affect contrast unless the tissues are being lost in noise (low CNR). Scan time scales directly with NEX/NSA and SNR as the square root of NEX/NSA.
The use of phase array coils allows the number of signal averages to be decreased with their superior SNR and resolution, thereby decreasing scan time.