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Partial Fourier Technique
 
The partial Fourier technique is a modification of the Fourier transformation imaging method used in MRI in which the symmetry of the raw data in k-space is used to reduce the data acquisition time by acquiring only a part of k-space data.
The symmetry in k-space is a basic property of Fourier transformation and is called Hermitian symmetry. Thus, for the case of a real valued function g, the data on one half of k-space can be used to generate the data on the other half.
Utilization of this symmetry to reduce the acquisition time depends on whether the MRI problem obeys the assumption made above, i.e. that the function being characterized is real.
The function imaged in MRI is the distribution of transverse magnetization Mxy, which is a vector quantity having a magnitude, and a direction in the transverse plane. A convenient mathematical notation is to use a complex number to denote a vector quantity such as the transverse magnetization, by assigning the x'-component of the magnetization to the real part of the number and the y'-component to the imaginary part. (Sometimes, this mathematical convenience is stretched somewhat, and the magnetization is described as having a real component and an imaginary component. Physically, the x' and y' components of Mxy are equally 'real' in the tangible sense.)
Thus, from the known symmetry properties for the Fourier transformation of a real valued function, if the transverse magnetization is entirely in the x'-component (i.e. the y'-component is zero), then an image can be formed from the data for only half of k-space (ignoring the effects of the imaging gradients, e.g. the readout- and phase encoding gradients).
The conditions under which Hermitian symmetry holds and the corrections that must be applied when the assumption is not strictly obeyed must be considered.
There are a variety of factors that can change the phase of the transverse magnetization:
Off resonance (e.g. chemical shift and magnetic field inhomogeneity cause local phase shifts in gradient echo pulse sequences. This is less of a problem in spin echo pulse sequences.
Flow and motion in the presence of gradients also cause phase shifts.
Effects of the radio frequency RF pulses can also cause phase shifts in the image, especially when different coils are used to transmit and receive.
Only, if one can assume that the phase shifts are slowly varying across the object (i.e. not completely independent in each pixel) significant benefits can still be obtained. To avoid problems due to slowly varying phase shifts in the object, more than one half of k-space must be covered. Thus, both sides of k-space are measured in a low spatial frequency range while at higher frequencies they are measured only on one side. The fully sampled low frequency portion is used to characterize (and correct for) the slowly varying phase shifts.
Several reconstruction algorithms are available to achieve this. The size of the fully sampled region is dependent on the spatial frequency content of the phase shifts. The partial Fourier method can be employed to reduce the number of phase encoding values used and therefore to reduce the scan time. This method is sometimes called half-NEX, 3/4-NEX imaging, etc. (NEX/NSA). The scan time reduction comes at the expense of signal to noise ratio (SNR).
Partial k-space coverage is also useable in the readout direction. To accomplish this, the dephasing gradient in the readout direction is reduced, and the duration of the readout gradient and the data acquisition window are shortened.
This is often used in gradient echo imaging to reduce the echo time (TE). The benefit is at the expense in SNR, although this may be partly offset by the reduced echo time. Partial Fourier imaging should not be used when phase information is eligible, as in phase contrast angiography.

See also acronyms for 'partial Fourier techniques' from different manufacturers.
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Spoiled Gradient Echo SequenceInfoSheet: - Sequences - 
Intro, 
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etc.MRI Resource Directory:
 - Sequences -
 
Spoiled gradient echo sequences use a spoiler gradient on the slice select axis during the end module to destroy any remaining transverse magnetization after the readout gradient, which is the case for short repetition times.
As a result, only z-magnetization remains during a subsequent excitation. This types of sequences use semi-random changes in the phase of radio frequency pulses to produce a spatially independent phase shift.
Companies use different acronyms to describe certain techniques.

Different terms for these gradient echo pulse sequences:
CE-FFE-T1 Contrast Enhanced Fast Field Echo with T1 Weighting,
GFE Gradient Field Echo,
FLASH Fast Low Angle Shot,
PS Partial Saturation,
RF spoiled FAST RF Spoiled Fourier Acquired Steady State Technique,
RSSARGE Radio Frequency Spoiled Steady State Acquisition Rewound Gradient Echo
S-GRE Spoiled Gradient Echo,
SHORT Short Repetition Techniques,
SPGR Spoiled Gradient Recalled (spoiled GRASS),
STAGE T1W T1 weighted Small Tip Angle Gradient Echo,
T1-FAST T1 weighted Fourier Acquired Steady State Technique,
T1-FFE T1 weighted Fast Field Echo.
In this context, 'contrast enhanced' refers to the pulse sequence, it does not mean enhancement with a contrast agent.
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• View the DATABASE results for 'Spoiled Gradient Echo Sequence' (11).Open this link in a new window

 
Further Reading:
  News & More:
3-D VOLUMETRIC IMAGING FOR STEREOTACTIC LESIONAL AND DEEP BRAIN STIMULATION SURGERY
Cutting Edge Imaging of THE Spine
February 2007   by www.pubmedcentral.nih.gov    
MRI Resources 
Resources - Shielding - MRI Technician and Technologist Jobs - Claustrophobia - Colonography - Stent
 
Superparamagnetic Iron OxideInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
(SPIO) Relatively new types of MRI contrast agents are superparamagnetic iron oxide-based colloids (median diameter greater than 50nm). These compounds consist of nonstoichiometric microcrystalline magnetite cores, which are coated with dextrans (in ferumoxide) or siloxanes (in ferumoxsil). After injection they accumulate in the reticuloendothelial system (RES) of the liver (Kupffer cells) and the spleen. At low doses circulating iron decreases the T1 time of blood, at higher doses predominates the T2* effect.
SPIO agents are much more effective in MR relaxation than paramagnetic agents. Since hepatic tumors either do not contain RES cells or their activity is reduced, the contrast between liver and lesion is improved. Superparamagnetic iron oxides cause noticeable shorter T2 relaxation times with signal loss in the targeted tissue (e.g., liver and spleen) with all standard pulse sequences. Magnetite, a mixture of FeO and Fe2O3, is one of the used iron oxides. FeO can be replaced by Fe3O4.
Use of these colloids as tissue specific contrast agents is now a well-established area of pharmaceutical development. Feridex®, Endorem™, GastroMARK®, Lumirem®, Sinerem®, Resovist® and more patents pending tell us that the last word in this area is not said.
Some remarkable points using SPIO:
A minimum delay of about 10 min. between injection (or infusion) and MR imaging, extends the examination time.
Cross-section flow void in narrow blood vessels may impede the differentiation from small liver lesions.
Aortic pulsation artifacts become more pronounced.


See also Superparamagnetism, Superparamagnetic Contrast Agents and Classifications, Characteristics, etc..
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• View the DATABASE results for 'Superparamagnetic Iron Oxide' (32).Open this link in a new window


• View the NEWS results for 'Superparamagnetic Iron Oxide' (3).Open this link in a new window.
 
Further Reading:
  Basics:
IMAGE CONTRAST IN MRI(.pdf)
   by www.assaftal.com    
  News & More:
How to stop using gadolinium chelates for magnetic resonance imaging: clinical-translational experiences with ferumoxytol
Saturday, 5 February 2022   by www.ncbi.nlm.nih.gov    
Polysaccharide-Core Contrast Agent as Gadolinium Alternative for Vascular MR
Monday, 8 March 2021   by www.diagnosticimaging.com    
Poly (dopamine) coated superparamagnetic iron oxide nanocluster for noninvasive labeling, tracking, and targeted delivery of adipose tissue-derived stem cells
Tuesday, 5 January 2016   by www.nature.com    
Longitudinal MRI contrast enhanced monitoring of early tumour development with manganese chloride (MnCl2) and superparamagnetic iron oxide nanoparticles (SPIOs) in a CT1258 based in vivo model of prostate cancer
Wednesday, 11 July 2012   by www.biomedcentral.com    
Searchterm 'ffe' was also found in the following services: 
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T2 WeightedForum -
related threads
 
Often used to indicate an image where most of the contrast between tissues or tissue states is due to differences in tissue T2 created typically by using longer TE and TR times.
This term may be misleading in that the potentially important effects of tissue density differences and the range of tissue T2 values are often ignored.
Choosing the machine parameters such that TR greater than T1 (typically greater than 2 000 ms) and TE less than T2 (typically greater than 100 ms) and noting that (1-exp(-TR/T1) = 1 for TR/T1 much greater than 1, will reduce Eq. 1 to the expression
Mxy = Mxy0exp(-TE/T2)
which is dependent on T2 only, hence the term T2 weighting. Therefore T2 weighted image contrast state is approached by imaging with a TR long compared to tissue T1 (to reduce T1 contribution to image contrast) and a TE between the longest and shortest tissue T2s of interest. A TR greater than 3 times the longest T1 is required for the T1 effect to be less than 5%. Due to the wide range of T1 and T2 and tissue density values that can be found in the body, an image that is T2 weighted for some tissues may not be so for others.
See also T2 Time.
Lesions with short T2 are (dark in T2 weighted sequences):
acute haemorrhage (deoxyHb)
haemosiderin
physiologic iron (basal ganglia, etc.)
mucinous lesions.
 
Images, Movies, Sliders:
 MRI Pancreas T2  Open this link in a new window
    
 Anatomic MRI of the Neck  Open this link in a new window
    
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 MRI Liver T2  Open this link in a new window
    
 
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• View the DATABASE results for 'T2 Weighted' (46).Open this link in a new window


• View the NEWS results for 'T2 Weighted' (1).Open this link in a new window.
 
Further Reading:
  Basics:
A paired dataset of T1- and T2-weighted MRI at 3 Tesla and 7 Tesla
Thursday, 27 July 2023   by www.nature.com    
Clinical evaluation of a speed optimized T2 weighted fast spin echo sequence at 3.0 T using variable flip angle refocusing, half-Fourier acquisition and parallel imaging
Wednesday, 25 October 2006
Fast T2 weighted imaging by PSIF at 0.2T for interventional MRI.(.pdf)
   by cds.ismrm.org    
  News & More:
Single Sequence Magnetic Resonance Imaging in Serous Otitis Media
Friday, 28 April 2023   by www.cureus.com    
Non-metallic T2-MRI agents based on conjugated polymers
Monday, 11 April 2022   by www.nature.com    
MRI T2 Mapping of the Knee Providing Synthetic Morphologic Images: Comparison to Conventional Turbo Spin-Echo MRI
Tuesday, 1 October 2019   by pubs.rsna.org    
New MRI technique offers faster diagnosis of multiple sclerosis
Monday, 1 February 2016   by medicalxpress.com    
MRI Resources 
Process Analysis - Collections - Image Quality - Crystallography - Coils - Liver Imaging
 
Apparent Diffusion CoefficientInfoSheet: - Artifacts - 
Case Studies, 
Reduction Index, 
etc.MRI Resource Directory:
 - Diffusion Weighted Imaging -
 
(ADC) A diffusion coefficient to differentiate T2 shine through effects or artifacts from real ischemic lesions. In the human brain, water diffusion is a three-dimensional process that is not truly random because the diffusional motion of water is impeded by natural barriers. These barriers are cell membranes, myelin sheaths, white matter fiber tracts, and protein molecules.
The apparent water diffusion coefficients can be calculated by acquiring two or more images with a different gradient duration and amplitude (b-values). The contrast in the ADC map depends on the spatially distributed diffusion coefficient of the acquired tissues and does not contain T1 and T2* values.
The increased sensitivity of diffusion-weighted MRI in detecting acute ischemia is thought to be the result of the water shift intracellularly restricting motion of water protons (cytotoxic edema), whereas the conventional T2 weighted images show signal alteration mostly as a result of vasogenic edema.
The reduced ADC value also could be the result of decreased temperature in the nonperfused tissues, loss of brain pulsations leading to a decrease in apparent proton motion, increased tissue osmolality associated with ischemia, or a combination of these factors. The lower ADC measurements seen with early ischemia, have not been fully established, however, a lower apparent ADC is a sensitive indicator of early ischemic brain at a stage when ischemic tissue remains potentially salvageable.

See also Diffusion Weighted Imaging and Diffusion Tensor Tractography.
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• View the DATABASE results for 'Apparent Diffusion Coefficient' (4).Open this link in a new window

 
Further Reading:
  Basics:
Implementation of Dual-Source RF Excitation in 3 T MR-Scanners Allows for Nearly Identical ADC Values Compared to 1.5 T MR Scanners in the Abdomen
Wednesday, 29 February 2012   by www.plosone.org    
EVALUATION OF HUMAN STROKE BY MR IMAGING
2000
  News & More:
The utility of texture analysis of kidney MRI for evaluating renal dysfunction with multiclass classification model
Tuesday, 30 August 2022   by www.nature.com    
Diffusion-weighted MRI in Advanced Epithelial Ovarian Cancer: Apparent Diffusion Coefficient as a Response Marker
Tuesday, 1 October 2019   by pubs.rsna.org    
EORTC study aims to qualify ADC as predictive imaging biomarker in preoperative regimens
Monday, 4 January 2016   by www.eurekalert.org    
Novel MRI Technique Could Reduce Breast Biopsies, University of Washington Study
Tuesday, 2 October 2012   by www.eurekalert.org    
Hopkins researchers use diffusion MRI technique to monitor ultrasound uterine fibroid treatment
Monday, 8 August 2005   by www.eurekalert.org    
MRI Resources 
Nerve Stimulator - Distributors - Chemistry - Resources - MRI Physics - Universities
 
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