![](gifs/layer2.gif) | Info Sheets |
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![](gifs/os_007.gif) | Out- side |
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(DE FGRE, Dual/ FFE, DE FFE) Simultaneously acquired in and out of phase TE gradient echo images. To quantitatively measure the signal intensity di fferences between out of phase and in phase images the parameters should be the same except for the TE.
The chemical shift artifact appearing on the out-of-phase image allows for the detection of lipids in the liver or adrenal gland, such as diffuse fatty infiltration, focal fatty infiltration, focal fatty sparing, benign adrenocortical masses and intracellular lipids within a hepatocellar neoplasm, where spin echo and fat suppression techniques are not as sensitive. Specific pathologies that have been reported include liver lipoma, angiomyolipoma, myelolipoma, metastatic liposarcoma, teratocarcinoma, melanoma, haemorrhagic neoplasm and metastatic choriocarcinoma. | | | | ![spacer](gifs/nb.gif) | | | Further Reading: | News & More:
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Some dyamides are under preclinical development as intravascular MRI contrast agents for blood flow perfusion.
Short name: Dy-DTPA-BMA, generic name: Sprodyamide, central moiety: Dy2+, contrast effect: T2*enhanced, relaxivity: r1=3.4, r2=3.8, B0=0.47,
Short name: Dy-DTPA, central moiety: Dy2+, contrast effect: T2*enhanced,
Short name: Albumin-(Dy-DTPA)x, central moiety: Dy2+, contrast effect: T2*enhanced.
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(FAT SAT) A specialized technique that selectively saturates fat protons prior to acquiring data as in standard sequences, so that they produce a negligible signal. The presaturation pulse is applied prior to each slice selection. This technique requires a very homogeneous magnetic field and very precise frequency calibration.
Fat saturation does not work well on inhomogeneous volumes of tissue due to a change in the precessional frequencies as the di fference in volume a ffects the magnetic field homogeneity. The addition of a water bag simulates a more homogeneous volume of tissue, thus improving the fat saturation. Since the protons in the water bag are in motion due to recent motion of the bag, phase ghosts can be visualized.
Fat saturation can also be difficult in a region of metallic prosthesis. This is caused by an alteration in the local magnetic field resulting in a change to the precessional frequencies, rendering the chemical saturation pulses ine ffective.
See also Fat Suppression, and Dixon. | | | | ![spacer](gifs/nb.gif) | | • View the DATABASE results for 'Fat Saturation' (9).![Open this link in a new window](gifs/nw3_g.gif)
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Fat suppression is the process of utilizing specific MRI parameters to remove the deleterious e ffects of fat from the resulting images , e.g. with STIR, FAT SAT sequences, water selective (PROSET WATS - water only selection, also FATS - fat only selection possible) excitation techniques, or pulse sequences based on the Dixon method.
Spin magnetization can be modulated by using special RF pulses. CHESS or its variations like SPIR, SPAIR ( Spectral Selection Attenuated Inversion Recovery) and FAT SAT use frequency selective excitation pulses, which produce fat saturation.
Fat suppression techniques are nearly used in all body parts and belong to every standard MRI protocol of joints like knee, shoulder, hips, etc.
Image Guidance
Imaging of, e.g. the foot can induce bad fat suppression with SPIR/FAT SAT due to the asymmetric volume of this body part. The volume of the foot alters the magnetic field to a di fferent degree than the smaller volume of the lower leg a ffecting the protons there. There is only a small band of tissue where the fat protons are precessing at the frequency expected, resulting in frequency selective fat saturation working only in that area. This can be corrected by volume shimming or creating a more symmetrical volume being imaged with water bags.
Even with their longer scan time and motion sensitivity, STIR (short T1/tau inversion recovery) sequences are often the better choice to suppress fat. STIR images are also preferred because of the decreased sensitivity to field inhomogeneities, permitting larger fields of views when compared to fat suppressed images and the ability to image away from the isocenter. See also Knee MRI.
Sequences based on Dixon turbo spin echo ( fast spin echo) can deliver a significant better fat suppression than conventional TSE/FSE imaging.
| | | | ![spacer](gifs/nb.gif) | | • View the DATABASE results for 'Fat Suppression' (28).![Open this link in a new window](gifs/nw3_g.gif)
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(Gd) Gadolinium is a Lanthanide element that is paramagnetic in its trivalent state.
This paramagnetic substance is used for MR imaging because of the e ffect of strongly decreasing the T1 relaxation times of the tissues to which gadolinium has access. When injected during magnetic resonance imaging, gadolinium will tend to change signal intensities by shortening the T1 time in its surroundings.
The relaxivity of gadolinium is an important measure of its efficacy, which is dependent on the chemical properties of the complex. The gadolinium ion cannot be used in its chloride, sulfate, or acetate forms because of poor tolerance and low solubility in water in the neutral pH range. Although toxic by itself, gadolinium can be given safely in a chelated form such as DTPA, that still retains much of its strong e ffect on relaxation times ( relaxivity).
See also Dotarem®, Gadovist®, MultiHance®, Omniscan®, OptiMARK®, and Contrast Agents, the info sheet gives an overview and more in-dept information about di fferent types of MRI contrast agents. | | | | ![spacer](gifs/nb.gif) | | • View the DATABASE results for 'Gadolinium' (66).![Open this link in a new window](gifs/nw3_g.gif)
| | | • View the NEWS results for 'Gadolinium' (17).![Open this link in a new window. Open this link in a new window.](gifs/nw3_g.gif)
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