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Partial SaturationInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
(PS) Excitation technique applying repeated RF pulses in times comparable to or shorter than T1. Incomplete T1 relaxation leads to reduction of the signal amplitude; there is the possibility of generating images with increased contrast between regions with different relaxation times.
Although partial saturation is also commonly referred to as saturation recovery, that term should properly be reserved for the particular case of partial saturation in which recovery after each excitation effectively takes place from true saturation. A GRE sequence where α = 90° is identical to the partial saturation or saturation recovery pulse sequence.
It does not directly produce images of T1. However, since the measured signal will depend on T1, the method generates contrast between regions with different relaxation times. If T2 and/or T2 effects are minimized through the use of a short echo time TE, the result is a T1 weighted image. It is not a T1 image due to the possible presence of spin density and T2 effects as well as the nonlinear dependence on T1.
The change in signal from a region resulting from a change in the interpulse time, TR, can be used to calculate T1 for the region.
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    • Partial Saturation Spin Echo
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Blood Flow Imaging - Coils - Veterinary MRI - Directories - Education pool - Breast Implant
 
Perfusion ImagingForum -
related threadsInfoSheet: - Sequences - 
Intro, 
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(PWI - Perfusion Weighted Imaging) Perfusion MRI techniques (e.g. PRESTO - Principles of Echo Shifting using a Train of Observations) are sensitive to microscopic levels of blood flow. Contrast enhanced relative cerebral blood volume (rCBV) is the most used perfusion imaging. Both, the ready availability and the T2* susceptibility effects of gadolinium, rather than the T1 shortening effects make gadolinium a suitable agent for use in perfusion imaging. Susceptibility here refers to the loss of MR signal, most marked on T2* (gradient echo)-weighted and T2 (spin echo)-weighted sequences, caused by the magnetic field-distorting effects of paramagnetic substances.
T2* perfusion uses dynamic sequences based on multi or single shot techniques. The T2* (T2) MRI signal drop within or across a brain region is caused by spin dephasing during the rapid passage of contrast agent through the capillary bed. The signal decrease is used to compute the relative perfusion to that region. The bolus through the tissue is only a few seconds, high temporal resolution imaging is required to obtain sequential images during the wash in and wash out of the contrast material and therefore, resolve the first pass of the tracer. Due to the high temporal resolution, processing and calculation of hemodynamic maps are available (including mean transit time (MTT), time to peak (TTP), time of arrival (T0), negative integral (N1) and index.
An important neuroradiological indication for MRI is the evaluation of incipient or acute stroke via perfusion and diffusion imaging. Diffusion imaging can demonstrate the central effect of a stroke on the brain, whereas perfusion imaging visualizes the larger 'second ring' delineating blood flow and blood volume. Qualitative and in some instances quantitative (e.g. quantitative imaging of perfusion using a single subtraction) maps of regional organ perfusion can thus be obtained.
Echo planar and potentially echo volume techniques together with appropriate computing power offer real time images of dynamic variations in water characteristics reflecting perfusion, diffusion, oxygenation (see also Oxygen Mapping) and flow.
Another type of perfusion MR imaging allows the evaluation of myocardial ischemia during pharmacologic stress. After e.g., adenosine infusion, multiple short axis views (see cardiac axes) of the heart are obtained during the administration of gadolinium contrast. Ischemic areas show up as areas of delayed and diminished enhancement. The MRI stress perfusion has been shown to be more accurate than nuclear SPECT exams. Myocardial late enhancement and stress perfusion imaging can also be performed during the same cardiac MRI examination.
 
Images, Movies, Sliders:
 Normal Lung Gd Perfusion MRI  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Left Circumflex Ischemia First-pass Contrast Enhancement  Open this link in a new window
 
Radiology-tip.comradPerfusion Scintigraphy
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Medical-Ultrasound-Imaging.comBolus Injection
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• View the DATABASE results for 'Perfusion Imaging' (16).Open this link in a new window


• View the NEWS results for 'Perfusion Imaging' (3).Open this link in a new window.
 
Further Reading:
  Basics:
CHAPTER 55: Ischemia
2003
EVALUATION OF HUMAN STROKE BY MR IMAGING
2000
  News & More:
Non-invasive diagnostic procedures for suspected CHD: Search reveals informative evidence
Wednesday, 8 July 2020   by medicalxpress.co    
Implementation of Dual-Source RF Excitation in 3 T MR-Scanners Allows for Nearly Identical ADC Values Compared to 1.5 T MR Scanners in the Abdomen
Wednesday, 29 February 2012   by www.plosone.org    
Motion-compensation of Cardiac Perfusion MRI using a Statistical Texture Ensemble(.pdf)
June 2003   by www.imm.dtu.dk    
Turbo-FLASH Based Arterial Spin Labeled Perfusion MRI at 7 T
Thursday, 20 June 2013   by www.plosone.org    
Measuring Cerebral Blood Flow Using Magnetic Resonance Imaging Techniques
1999   by www.stanford.edu    
Vascular Filters of Functional MRI: Spatial Localization Using BOLD and CBV Contrast
MRI Resources 
Movies - Breast Implant - Cardiovascular Imaging - Calculation - Jobs pool - Online Books
 
Spatial Resolution
 
The smallest distance between two points in the object that can be distinguished as separate details in the image, generally indicated as a length or a number of black and white line pairs per mm (lp/mm).
The specific criterion for resolution to be used, depends on the type of test used (e.g., bar pattern or contrast-detail phantom). As the ability to separate or detect objects depends on their contrast and the noise, and the different MR parameters of objects will affect image contrast differently for different imaging techniques, care must be taken in comparing the results of resolution phantom tests of different machines and no single simple measure of resolution can be specified.
The resolution may be an isotropic one. The resolution may be larger than the size corresponding to the discrete image element (pixel), although it cannot be smaller.
 
Images, Movies, Sliders:
 MRI - Anatomic Imaging of the Ankle 1  Open this link in a new window
    
SlidersSliders Overview

 Anatomic MRI of the Knee 1  Open this link in a new window
    
SlidersSliders Overview

 
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Further Reading:
  Basics:
Faster speed, better spatial resolution lead 3T benefits
   by sipi.usc.edu    
Musculoskeletal MRI at 3.0 T: Relaxation Times and Image Contrast
Sunday, 1 August 2004   by www.ajronline.org    
  News & More:
New Paradigm for Nanoscale Resolution MRI Experimentally Achieved
Friday, 27 September 2013   by www.sciencedaily.com    
3-D Virus Imaging wth Magnetic Resonance Force Microscopy
Wednesday, 14 January 2009   by www.medgadget.com    
Searchterm 'ffe' was also found in the following services: 
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Spine MRIMRI Resource Directory:
 - Spine MRI -
 
Magnetic resonance imaging (MRI) of the spine is a noninvasive procedure to evaluate different types of tissue, including the spinal cord, vertebral disks and spaces between the vertebrae through which the nerves travel, as well as distinguish healthy tissue from diseased tissue.
The cervical, thoracic and lumbar spine MRI should be scanned in individual sections. The scan protocol parameter like e.g. the field of view (FOV), slice thickness and matrix are usually different for cervical, thoracic and lumbar spine MRI, but the method is similar. The standard views in the basic spinal MRI scan to create detailed slices (cross sections) are sagittal T1 weighted and T2 weighted images over the whole body part, and transverse (e.g. multi angle oblique) over the region of interest with different pulse sequences according to the result of the sagittal slices. Additional views or different types of pulse sequences like fat suppression, fluid attenuation inversion recovery (FLAIR) or diffusion weighted imaging are created dependent on the indication.

Indications:
•
Neurological deficit, evidence of radiculopathy, cauda equina compression
•
Primary tumors or drop metastases
•
Infection/inflammatory disease, multiple sclerosis
•
Postoperative evaluation of lumbar spine: disk vs. scar
•
Evaluation of syrinx
•
Localized back pain with no radiculopathy (leg pain)

Contrast enhanced MRI techniques delineate infections vs. malignancies, show a syrinx cavity and support to differentiate the postoperative conditions. After surgery for disk disease, significant fibrosis can occur in the spine. This scarring can mimic residual disk herniation. Magnetic resonance myelography evaluates spinal stenosis and various intervertebral discs can be imaged with multi angle oblique techniques. Cine series can be used to show true range of motion studies of parts of the spine. Advanced open MRI devices are developed to perform positional scans in the position of pain or symptom (e.g. Uprightâ„¢ MRI formerly Stand-Up MRI).
 
Images, Movies, Sliders:
 Anatomic Imaging of the Lumbar Spine  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 
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• View the DATABASE results for 'Spine MRI' (11).Open this link in a new window


• View the NEWS results for 'Spine MRI' (4).Open this link in a new window.
 
Further Reading:
  Basics:
Newer Sequences for Spinal MR Imaging: Smorgasbord or Succotash of Acronyms?
   by www.ajnr.org    
Cutting Edge Imaging of THE Spine
February 2007   by www.pubmedcentral.nih.gov    
Landmark Independent Study by UCLA School of Medicine Reports Comparison of Dynamic™ Upright® MRI With Static Upright MRI in More Than 1,000 Patients (1,302):
Thursday, 15 November 2007   by www.fonar.com    
  News & More:
Recommendations for MRI Assessment in Managing Axial Spondyloarthritis
Wednesday, 8 January 2020   by www.rheumatologyadvisor.com    
MRI Of The Spine Identifies Smoldering Myeloma Patients At High Risk Of Progressing To Multiple Myeloma
Tuesday, 26 August 2014   by www.myelomabeacon.com    
Intensive training of young tennis players causes spinal damage
Wednesday, 18 July 2007   by www.eurekalert.org    
MRI Resources 
Equipment - NMR - Cardiovascular Imaging - Stimulator pool - Service and Support - Knee MRI
 
Cardiovascular ImagingMRI Resource Directory:
 - Cardiovascular Imaging -
 
Cardiovascular MR imaging includes the complete anatomical display of the heart with CINE imaging of all phases of the heartbeat. Ultrafast techniques make breath hold three-dimensional coverage of the heart in different cardiac axes feasible. Cardiac MRI provides reliable anatomical and functional assessment of the heart and evaluation of myocardial viability and coronary artery disease by a noninvasive diagnostic imaging technique.
Cardiovascular MRI offers potential advantages over radioisotopic techniques because it provides superior spatial resolution, does not use ionizing radiation, has no imaging orientations constraints and contrast resolution better than echocardiography. It also offers direct visualization and characterization of atherosclerotic plaques and diseased vessel walls and surrounding tissues in cardiovascular research.
MRI perfusion approaches measure the alteration of regional myocardial magnetic properties after the intravenous injection of contrast agents and assess the extent of injury after a myocardial infarction and the presence of myocardial viability with a technique based on late enhancement. Extracellular MRI contrast agents, like Gd-DTPA, accumulate only in irreversibly damaged myocardium after a time period of at least 10 minutes.
This type of patients may also have an implanted cardiac stent, bypass or a cardiac pacemaker and special caution should be observed on the MRI safety and the contraindications. While a number of coronary stents have been tested and reported to be MRI compatible, coronary stents must be assessed on an individual basis, with the medical team weighing the risks and benefits of the MRI procedure.

Cardiac MRI overview:
•
Myocardial perfusion imaging and viability
•
Calculation of ventricular volume, myocardial mass and wall thickness
•
Functional parameters
•
Description of a stenosis or aneurysma
•
Anatomical display of the heart, vessels and the surrounding tissue

Cardiovascular MRI has become one of the most effective noninvasive imaging techniques for almost all groups of heart and vascular disease.
 
Images, Movies, Sliders:
 Angulation of Cardiac Planes Cine Images of Septal Infarct  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Left Circumflex Ischemia First-pass Contrast Enhancement  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Delayed Myocardial Contrast Enhancement from Infarct  Open this link in a new window
 
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• View the DATABASE results for 'Cardiovascular Imaging' (18).Open this link in a new window


• View the NEWS results for 'Cardiovascular Imaging' (6).Open this link in a new window.
 
Further Reading:
  Basics:
Cardiac MRI - Technical Aspects Primer
Wednesday, 7 August 2002
Coronary Artery Disease: Combined Stress MR Imaging Protocol-One-Stop Evaluation of Myocardial Perfusion and Function1
   by radiology.rsnajnls.org    
A Guide To Cardiac Imaging
   by www.simplyphysics.com    
  News & More:
New Imaging Technique Reveals Different Heart Motions by Age, Gender
Thursday, 10 December 2009   by www.sciencedaily.com    
MRI Resources 
Safety Products - Colonography - Journals - Process Analysis - Safety Training - General
 
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