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Result : Searchterm 'paramagnetic' found in 10 terms [] and 91 definitions []
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Searchterm 'paramagnetic' was also found in the following services: 
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News  (9)  Resources  (5)  Forum  (3)  
 
GastroMARK®InfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
GastroMARK® belongs to the negative oral contrast agents (same as Lumirem®, another brand name for ferumoxsil). GastroMARK® is used to distinguish the loops of the bowel from other abdominal structures and physiology. When GastroMARK® is ingested, it flows through and darkens the stomach and the small intestine in 30 to 45 minutes. By more clearly identifying the intestinal loops, GastroMARK® improves visualization of adjacent abdominal tissues such as the pancreas.
Drug Information and Specification
NAME OF COMPOUND
Ferumoxsil, silicone-coated superparamagnetic iron oxide, USAN, AMI-121
CENTRAL MOIETY
Fe3+/Fe2+
CONTRAST EFFECT
T2*enhanced
r1=3.4, r2=3.8, B0=1.0T
PHARMACOKINETIC
Gastrointestinal
OSMOLALITY
250 mosm/kgH2O
CONCENTRATION
52.5mg Fe/300mL
DOSAGE
300 mL oral
PREPARATION
Finished product
INDICATION
Bowel marking
DEVELOPMENT STAGE
For sale
DISTRIBUTOR
See below
PRESENTATION
Bottles containing 300 mL
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Distribution Information
TERRITORY
TRADE NAME
DEVELOPMENT
STAGE
DISTRIBUTOR
USA
GastroMARK®
For sale
EU
For sale
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Further Reading:
  Basics:
ferumoxsil, oral suspension GastroMARK GastroMARK ®
MATERIAL SAFETY DATA SHEET
   by dailymed.nlm.nih.gov    
MRI Resources 
MRI Accidents - Guidance - Raman Spectroscopy - Databases - Calculation - Stimulator pool
 
Gastrointestinal ImagingMRI Resource Directory:
 - Abdominal Imaging -
 
Rectal staging is necessary for the preoperative assessment of intra- and extramural tumor infiltration or the decision for adjuvant radio-chemotherapy. One indication of MRI with luminal contrast enhancement is small bowel enteroclysis after duodenal intubation for visualization of inflammatory bowel wall thickening and other complications.
"Double contrast" enhancement of the bowel lumen is the administration of plain water or water with methylcellulose along with heavily T2 weighted sequences or contrast enhanced T1 weighted sequences.
Several oral contrast agents have been used for small bowel MRI: Mannitol, metamucil, locust bean gum, and PEG. All provide sufficient bowel distension and homogeneity, but suffer from side effects such as diarrhea. The volume of PEG or mannitol administered must be not too large in order to achieve the best compromise between distension and acceptance by the patient.
MR colonography with positive bowel lumen enhancement requires higher concentrations of paramagnetic agents compared to the available dedicated enteral contrast agents, IV compounds are used to dope water enemas for this purpose.
Some investigators advocate negative bowel enhancement with Contrast Agents to suppress high signal bowel content in MRCP ( Magnetic resonance cholangiopancreaticography ). The use of a mixture of metamucil and 20 ml of gadolinium chelate provides good homogeneity and good tolerance without diarrhea.
 
Images, Movies, Sliders:
 MR Colonography Gadolinium per Rectum  Open this link in a new window
      

Courtesy of  Robert R. Edelman
 Pregnancy and Small Bowel Obstruction  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 
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• View the DATABASE results for 'Gastrointestinal Imaging' (6).Open this link in a new window


• View the NEWS results for 'Gastrointestinal Imaging' (1).Open this link in a new window.
 
Further Reading:
  Basics:
Nottingham scientists exploit MRI technology to assist in the treatment of IBS
Thursday, 9 January 2014   by www.news-medical.net    
Hydro-MRI of the Small Bowel: Effect of Contrast Volume, Timing of Contrast Administration, and Data Acquisition on Bowel Distention
Sunday, 1 October 2006   by www.ajronline.org    
Usefulness of MR Imaging for Diseases of the Small Intestine: Comparison with CT
2000   by www.ncbi.nlm.nih.gov    
MRI Resources 
Developers - Corporations - Examinations - Safety Products - Hospitals - Functional MRI
 
Gd-2,5-BPA-DO3AInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Short name: Gd-2,5-BPA-DO3A, central moiety: Gd
A paramagnetic agent that undergo hepatic uptake and biliary excretion, therefore Gd-2,5-BPA-DO3A can act as a hepatospecific MRI contrast agent.
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Searchterm 'paramagnetic' was also found in the following services: 
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News  (9)  Resources  (5)  Forum  (3)  
 
HaemoglobinInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
(Hb) Haemoglobin is the major endogenous oxygen-binding molecule, responsible for binding oxygen in the lung and transporting it to the tissues by means of the circulation. Haemoglobin is contained in very high concentration in the red blood cells.
Haemoglobin is an Fe chelate tightly binding one Fe ion in its II oxidation state where it carries the charge 2+ (ferrous iron). If an oxygen molecule is bound to Hb, Hb is called oxyhaemoglobin, if no oxygen molecule is bound it is called deoxyhaemoglobin. When haemoglobin is oxidized (i.e. in a haematoma), Fe2+ is transformed into Fe3+. The resulting haemoglobin is then called metoxyhaemoglobin (Hb Fe3+).
Deoxyhaemoglobin and metoxyhaemoglobin act as paramagnetic contrast agents in MR, while oxyhaemoglobin is diamagnetic. This partly explains the special appearance of an aging haematoma in MR imaging and is also the basic of the blood oxygenation level dependent contrast (BOLD) used in functional magnetic resonance imaging of the brain (fMRI).
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• View the DATABASE results for 'Haemoglobin' (10).Open this link in a new window

 
Further Reading:
  Basics:
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
  News & More:
MRI effectively measures hemochromatosis iron burden
Saturday, 3 October 2015   by medicalxpress.com    
Iron overload: accuracy of in-phase and out-of-phase MRI as a quick method to evaluate liver iron load in haematological malignancies and chronic liver disease
Friday, 1 June 2012   by www.ncbi.nlm.nih.gov    
EVALUATION OF HUMAN STROKE BY MR IMAGING
2000
MRI Resources 
MRI Centers - Liver Imaging - Diffusion Weighted Imaging - Shoulder MRI - DICOM - Education
 
LumenHance®InfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Oral administration of this liposomal encapsulated manganese chloride results in a reduction of the T1 relaxation time causing enhanced signal on T1 weighted MR images. Bracco received marketing approval in December 1997 in the United States, but marketing state is still uncertain.

See also Classifications, Characteristics, etc.
Drug Information and Specification
NAME OF COMPOUND
MnCl2, Manganese chloride tetrahydrate
CENTRAL MOIETY
Mn2+
CONTRAST EFFECT
T1, Predominantly positive enhancement
Paramagnetic
PHARMACOKINETIC
Gastrointestinal
PREPARATION
Powder for reconstitution
INDICATION
Bowel marking
DEVELOPMENT STAGE
For sale
DISTRIBUTOR
See below
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Distribution Information
TERRITORY
TRADE NAME
DEVELOPMENT
STAGE
DISTRIBUTOR
LumenHance®
for sale
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• View the DATABASE results for 'LumenHance®' (4).Open this link in a new window

MRI Resources 
Used and Refurbished MRI Equipment - Liver Imaging - Pediatric and Fetal MRI - Service and Support - Spectroscopy pool - Crystallography
 
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