Many MR imaging techniques using Motion Probing Gradients (MPG's) such as Spin Echo (SE), Stimulated Echo (STE), Rapid Acquisition with Relaxation Enhancement (RARE), Turbo-SE, and SE-EPI (Echo Planar Imaging for Spin echo acquisition), Spiral imaging, and Projection reconstruction including PROPELLER are applicable to DWI. In diffusion weighted imaging, 2 MPG's are required. The MPG's are put symmetrically into both sides of a 180° or 90° RF pulse to change the direction of the magnetized spin in the X-Y plane for spin echo or stimulated echo acquisition.

Multi echo imaging sequences use a series of echoes acquired as a train following after a single excitation pulse. Multiple symmetrical or asymmetrical echoes can be acquired, typically T2 weighted. In spin echo imaging, each echo is formed by a 180° pulse, but also a FSE (TSE, RARE) or EPI sequence can be used. As a difference to a normal fast spin echo sequence, in multi echo imaging, separate images are produced from each echo of the train with different T2 weightings. The signal height reduces with transverse relaxation. This drop in signal can be used to calculate a pure T2 image.

See also Fast Spin Echo.

(MLSI) Variations of sequential line imaging techniques that can be used if selective excitation methods that do not affect adjacent lines are employed. Adjacent lines are imaged while waiting for relaxation of the first line toward equilibrium, which may result in decreased image acquisition time. A different type of MLSI uses simultaneous excitation of two or more lines with different phase encoding followed by suitable decoding.

A usual variation of sequential plane imaging technique that can be used with selective excitation technique that does not affect adjacent slices. Since, in SE imaging TR longer than TE, the machine would be idling most of the time, if a single slice would be acquired; multiple slice imaging was introduced early on. Adjacent slices are imaged while waiting for relaxation of the first slice toward equilibrium, resulting in decreased image acquisition time for the set of slices. The maximum number of slices of a pulse sequence depends on the repetition time.

Categories of negative oral contrast agents:
Negative oral contrast media are usually based on superparamagnetic particles and act by inducing local field inhomogeneities, which results in shortening of both T1 and T2 relaxation times. Superparamagnetic contrast agents have predominant T2 weighted effects. Biphasic contrast media are agents that have different signal intensities on different sequences, depending on the concentration at which they are used.
Suitable materials for oral contrast agents should have little or no absorption by the stomach or intestines, complete excretion, no motion or susceptibility artifacts, affordability, and uniform marking of the gastrointestinal tract. Benefits of negative oral contrast agents are the reduction of ghosting artifacts caused by the lack of signal. Superparamagnetic iron oxides produce also in low concentrations a noticeable signal loss; but can generate susceptibility artifacts especially in gradient echo sequences. Perfluorochemicals do not dilute in the bowel because they are not miscible with water.
High cost, poor availability, and limited evaluations of side effects are possible disadvantages.
Negative oral contrast agents are used e.g., in MRCP, where the ingestion of 600-900 ml of SPIO cancels out the signal intensity of the lumen (in addition after the injection of a gadolinium-based contrast medium, the enhancement of the inflammatory tissues is clearer seen), and in MR abdominal imaging of Crohn's disease in combination with mannitol.

Blueberry or pineapple juices are useable for examinations of the pancreas (MRCP, upper abdominal imaging) as cheep contrast agents, because of the content of magnetic substances (e.g. manganese).

See also Ferristene, Ferumoxsil, Oral Magnetic Particles, Gastrointestinal Imaging.