(GRASS) This sequence is very similar to FLASH, except that the spoiler pulse is eliminated. As a result, any transverse magnetization still present at the time of the next RF pulse is incorporated into the steady state. GRASS uses a RF pulse that alternates in sign. Because there is still some remaining transverse magnetization at the time of the RF pulse, a RF pulse of a degree flips the spins less than a degree from the longitudinal axis. With small flip angles, very little longitudinal magnetization is lost and the image contrast becomes almost independent of T1. Using a very short TE eliminates T2* effects, so that the images become proton density weighted. As the flip angle is increased, the contrast becomes increasingly dependent on T1 and T2*. It is in the domain of large flip angles and short TR that GRASS exhibits vastly different contrast to FLASH type sequences.

The term in phase refers to an image in which the signals from two spectral components (such as fat and water) add constructively in a voxel. T1 weighted in phase images are acquired by a gradient echo-based technique with a short TR, TE and a high flip angle greater than 60 degrees. To some degree, in phase sequences are more sensitive to detection of focal hepatic lesions than out of phase for evaluating reduced lesion-to-liver contrast, but the choice for a T1 gradient echo sequence is still based on field strength, advanced imaging techniques (breath hold imaging), and physician preference.

The incoherent gradient echo (gradient spoiled) type of sequence uses a continuous shifting of the RF pulse to spoil the remaining transverse magnetization. The transverse magnetization is destroyed by a magnetic field gradient. This results in a T1 weighted image. Spoiling can be accomplished by RF or a gradient.
Gradient spoiling occurs after each echo by using strong gradients in the slice-select direction after the frequency encoding and before the next RF pulse. Because spins in different locations in the magnet thereby experience a variety of magnetic field strengths, they will precess at differing frequencies; as a consequence they will quickly become dephased. Magnetic field gradients are not very efficient at spoiling the transverse steady state. To be effective, the spins must be forced to precess far enough to become phased randomly with respect to the RF excitation pulse. In clinical MRI machines, the field gradients are set up in such a way that they increase and decrease relative to the center of the magnet; the magnetic field at the magnet 'isocenter' does not change.
The T1 weighting increases with the flip angle and the T2* weighting increases with echo time (TE). Typical repetition time (TR) are 30-500 ms and TE less than 15 ms.

See also Ernst Angle.

From Philips Medical Systems; the Intera-family offers with this mid field system maximum efficiency, flexibility and performance. All Philips MR products contain SENSE (coil SENSitivity Encoding) technology - that increases scanning speed.

From Philips Medical Systems;
the Intera-family offers with this member a wide range of possibilities, efficiency and a ergonomic and intuitive serving-platform. Also available as Intera CV for cardiac and Intera I/T for interventional MR procedures.
The scanners are also equipped with SENSE technology, which is essential for high-quality contrast enhanced magnetic resonance angiography, interactive cardiac MR and diffusion tensor imaging (DTI) fiber tracking.
The increased accuracy and clarity of MR scans obtained with this technology allow for faster and more accurate diagnosis of potential problems like patient friendliness and expands the breadth of applications including cardiology, oncology and interventional MR.