Crosstalk is an artifact introduced into images by interference between adjacent slices of a scan, caused by a slice profile that is not ideal due to the constraints of the measurement technology. If the slice distances are too small, there is cross talk between the slices, which can affect T1contrast.
Image Guidance
This artifact can be eliminated by limiting the minimum spacing (for the most sequences a minimum gap 10% and for IR sequences 20%) between the slices. Crosstalk can also be reduced by selection of interleaved slices (so a slice gap will not be necessary), but interleaved data acquisition can produce large mean intensity differences between adjacent slices.
Diffusion weighted imaging can be performed similar to the phase contrast angiography sequence. The gradients must be increased in amplitude to depict the much slower motions of molecular diffusion in the body.
While a T1 weightedMRIpulse sequence is diffusion sensitive, a quantitative diffusionpulse sequence was introduced by Steijskal and Tanner. Its characteristic features are two strong symmetrical gradient lobes placed on either side of the 180° refocusing pulse in a spin echosequence. These symmetrical gradient lobes have the sole purpose of enhancing dephasing of spins, thereby accelerating intravoxel incoherent motion (IVIM) signal loss.
Dephasing is proportional to the square of the time (diffusion time) during which the gradients are switched on and the strength of the applied gradient field. Therefore, the use of high field gradient systems with faster and more sensitive sequences, make diffusion weighting more feasible.
Areas in which the protons diffuse rapidly (swollen cells in early stroke, less restriction to diffusion) will show an increased signal when the echo is measured relative to areas in which diffusion is restricted.
For increased accuracy of diffusion measurement and image enhancement, useful motion correction techniques such as navigator echo and other methods should be used. In addition to this, applying the b-value calculated by the strength and duration of motion probing gradients with a high rate of accuracy is very important.
WARNING: NEPHROGENIC SYSTEMIC FIBROSIS
Gadolinium-based contrast agents increase the risk for nephrogenic systemic fibrosis (NSF) in patients with acute or chronic severe renal insufficiency (glomerular filtration rate less than 30 mL/min/1.73m2), or acute renal insufficiency of any severity due to the hepato-renal syndrome or in the perioperative liver transplantation period.
In fast imaging sequences driven equilibrium sensitizes the sequence to variations in T2. This MRI technique turns transverse magnetization Mxy to the longitudinal axis using a pulse rather than waiting for T1 relaxation.
The first two pulses form a spin echo and, at the peak of the echo, a second 90° pulse returns the magnetization to the z-axis in preparation for a fresh sequence.
In the absence of T2 relaxation, then all the magnetization can be returned to the z-axis. Otherwise, T2 signal loss during the sequence will reduce the final z-magnetization.
The advantage of this sequence type is, that both longitudinal and also transverse magnetization are back to equilibrium in a shorter amount of time. Therefore, contrast and signal can be increased while using a shorter TR. This pulse type can be applied to other sequences like FSE, GE or IR.
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