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 'Feridex°' 
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MRI Resources 
MR Myelography - Libraries - Liver Imaging - Implant and Prosthesis pool - General - Sequences
 
Feridex°InfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
A brand name for ferumoxide (same as Endorem™)
Feridex® is a sterile aqueous colloid of superparamagnetic iron oxide associated with dextran for intravenous administration as a MRI contrast medium for the detection of liver lesions that are associated with an alteration in the RES.
Feridex® is taken up by macrophages, found only in healthy liver cells but not in most tumors. Tissues such as metastases, primary liver cancer, cysts and various benign tumors, adenomas and hyperplasia retain their native signal intensity, so the contrast between normal and abnormal tissue is increased. Feridex® is a black to reddish-brown aqueous colloid.
See also Ferumoxide.

In November 2008, AMAG Pharmaceuticals, Inc. decided to discontinue the manufacturing of Feridex.
Drug Information and Specification
NAME OF COMPOUND
Dextran-coated ferumoxide, Ami-25
CENTRAL MOIETY
Fe2+/Fe3+
CONTRAST EFFECT
T2, predominantly negative enhancement
r1=40.0, r2=160, B0=0.47T
PHARMACOKINETIC
RES-directed
340 mosm/kgH2O
CONCENTRATION
11.2mg Fe/ml
DOSAGE
15 µmol Fe/kg
PREPARATION
Suspend in an isotonic glucose solution
INDICATION
DEVELOPMENT STAGE
For sale
DISTRIBUTOR
See below
PRESENTATION
Ampoule of 8 mL
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Distribution Information
TERRITORY
TRADE NAME
DEVELOPMENT
STAGE
DISTRIBUTOR
USA
-
-
EU
Brazil
for sale ?
Argentina
for sale ?
South Korea
for sale ?
Israel
for sale ?
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Further Reading:
  Basics:
AMAG Pharmaceuticals Inc. Q4 2008 Earnings Call Transcript
Friday, 27 February 2009   by seekingalpha.com    
Feridex Prescribing Information(.pdf)
   by berlex.bayerhealthcare.com    
  News & More:
MAGNETIC RESONANCE IMAGING OF FOCAL LIVER LESIONS(.pdf)
2002
MRI Resources 
Non-English - Health - Lung Imaging - Shielding - Process Analysis - Veterinary MRI
 
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