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Full Width at Tenth Maximum
 
(FWTM) The width of a Gaussian or Lorentzian type curve at the tenth of its maximum height (full width at half maximum (FWHM)) and a quality measure of the sharpness of a peak (frequency peak, resolution peak) used less frequently than the FWHM measure.
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Functional Brain MR SpectroscopyMRI Resource Directory:
 - Functional MRI -
 
The use of MR spectroscopy for acquiring functional activation of the brain.
There are two possible approaches:
In the first, localized spectra of brain water are acquired and subtle changes in these spectra reflect the biophysical water environment. Changes in T2 due to deoxyhaemoglobin concentration may be detected in this way. The disadvantages of poor spatial resolution are to some extent offset by the high signal to noise ratio SNR of the spectroscopic data.
An alternative approach is to use MR spectroscopy directly to detect metabolites that are altered by brain activation. These include lactate and glucose. Such experiments have inherently poor spatial and temporal resolution, but do give a direct indication of the metabolic response of the brain to functional activation.
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Functional Magnetic Resonance ImagingMRI Resource Directory:
 - Functional MRI -
 
(fMRI) Functional magnetic resonance imaging is a technique used to determine the dynamic brain function, often based on echo planar imaging, but can also be performed by using contrast agents and observing their first pass effects through brain tissue. Functional magnetic resonance imaging allows insights in a dysfunctional brain as well as into the basic workings of the brain.
The in functional brain MRI most frequently used effect to assess brain function is the blood oxygenation level dependent contrast (BOLD) effect, in which differential changes in brain perfusion and their resultant effect on the regional distribution of oxy- to deoxyhaemoglobin are observable because of the different 'intrinsic contrast media' effects of the two haemoglobin forms. Increased brain activity causes an increased demand for oxygen, and the vascular system actually overcompensates for this, increasing the amount of oxygenated haemoglobin. Because deoxygenated haemoglobin attenuates the MR signal, the vascular response leads to a signal increase that is related to the neural activity.
Functional imaging relates body function or thought to specific locations where the neural activity is taking place. The brain is scanned at low resolution but at a fast rate (typically once every 2-3 seconds). Structural MRI together with fMRI provides an anatomical baseline and best spatial resolution.
Interactions can also be seen from the motor cortex to the cerebellum or basal ganglia in the case of a movement disorder such as ataxia. For example: by a finger movement the briefly increase in the blood circulation of the appropriate part of the brain controlling that movement, can be measured.
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• View the NEWS results for 'Functional Magnetic Resonance Imaging' (15).Open this link in a new window.

• View the DATABASE results for 'Functional Magnetic Resonance Imaging' (8).Open this link in a new window

 
Further Reading:
  Basics:
IMAGE CONTRAST IN MRI(.pdf)
   by www.assaftal.com    
  News & More:
New AI application reads eye movements
Tuesday, 16 November 2021   by www.news-medical.net    
Functional MRI Can Provide Clearer Picture of Unresponsive COVID-19 Patient's Brain Function and Potential for Recovery
Tuesday, 26 January 2021   by www.hospimedica.com    
Scientists first studied the brain of birds while moving
Sunday, 20 September 2020   by freenews.live    
MRI Technique Used to Identify Future Risk of Binge Drinking
Monday, 6 January 2020   by www.diagnosticimaging.com    
Functional MRI may help identify new, effective painkillers for chronic pain sufferers
Thursday, 4 February 2016   by www.eurekalert.org    
Study shows functional MRI differences in working memory in people with primary insomnia
Saturday, 31 August 2013   by www.news-medical.net    
Functional magnetic resonance imaging may improve diagnosis of autism
Tuesday, 31 May 2011   by www.dnaindia.com    
Using fMRI to study brain development
Friday, 30 November 2007   by www.eurekalert.org    
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